HBV Pre-S
目录号 : GP25335Hepatitis B Virus Pre-S Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Protein is >95% pure as determined by 12% PAGE (coomassie staining). | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered solution. | Shipping Condition | Shipped with Ice Packs. |
| Stability | HBV Pre-S although stable at 4°C for 1 week, should be stored below -18°C .Please prevent freeze thaw cycles. | ||
| Formulation | Sterile Filtered solution containing PBS, 1M urea and 0.05% sodium azide. | ||
Hepatitis B virus surface gene encodes 3 proteins: small (HBs), middle (MHBs) and large (LHBs) surface protein. These 3 proteins are translated from distinct start codons, however share a common reading frame and stop codon. HBs contains 226 amino acids, it is a major viral envelope component. MHBs has extra 55 amino acids (Pre-S2) located to the N-terminus of HBs, LHBs has an additional 119 amino acids (Pre-S1). Pre-S is a region is comprised of Pre-S1 and S2, Pre-S1 has a vital role in receptor recognition, while Pre-S2 plays a part in translocation of virus into host cell. Clinically, HBV pre-S is linked with HBsAg and HBV DNA copies, which indicates active replication of virus, reduction of pre-S is typically associated with decreased HBV DNA copies, pointing to an improved predictor of treatment. In addition, Pre-S is a potential vaccine under development to enhance currently used HBsAg vaccine.
Purified by proprietary chromatographic technique.
Immunoassay.
HBV Pre-S although stable at 4°C for 1 week, should be stored below -18°C .Please prevent freeze thaw cycles.