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HCV NS3 His

目录号 : GP25277

Hepatitis C Virus NS3 Recombinant, His Tag

HCV NS3 His Chemical Structure

规格 价格 库存 购买数量
20μg
¥2,310.00
5-10工作日
100μg
¥9,240.00
5-10工作日
1mg
¥50,400.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

The E.coli derived recombinant protein contains a total of 268 amino acids having a Mw of 27.9 kDa. The protein contains the HCV NS3 immunodominant regions, amino acids 1225-1456. The HCV NS3 protein is fused to a 36 His Tag at N-terminus and purified by standard chromatography techniques.

Product Data

Purity Protein is >95% pure as determined by SDS-PAGE. Source
Phycical Appearance Shipping Condition Shipped with Ice Packs.
Amino Acid Sequence MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSVAHL HAPTGSGKST KVPAAYAAQG YKVLVLNPSV AATLGFGAYM SKAHGVDPNI RTGVRTITTG SPITYSTYGK FLADGGCSGG AYDIIICDEC HSTDATSILG IGTVLDQAET AGARLVVLAT ATPPGSVTVS HPNIEEVALS TTGEIPFYGK AIPLEVIKGG RHLIFCHSKK KCDELAAKLV ALGINAVAYY RGLDVSVIPT SGDVVVVSTD ALMTGFTGDF DSVIDCNT.
Stability HCV-NS3 His although stable at 4°C for 1 week, should be stored below -18°C . Please prevent freeze thaw cycles.
Formulation HCV NS3 in 20mM Tris-HCl pH-8, 1mM DTT & 10% Glycerol.

Introduction

HCV is a small 50nm, enveloped, single-stranded, positive sense RNA virus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host''s immune response. Hepatitis C virus is classified into six genotypes (1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).

Stability

HCV-NS3 His although stable at 4°C for 1 week, should be stored below -18°C . Please prevent freeze thaw cycles.