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HCV NS4 (1916-1947 a.a.)

目录号 : GP25283

Hepatitis C Virus NS4 (1916-1947 a.a.) Recombinant

HCV NS4 (1916-1947 a.a.) Chemical Structure

规格 价格 库存 购买数量
100μg
¥2,310.00
5-10工作日
500μg
¥9,240.00
5-10工作日
1mg
¥18,900.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

E.coli derived 30 kDa recombinant protein. Artificial mosaic polypeptide composite constructed from diagnostically relevant antigenic regions derived from the NS4 region.

Product Data

Purity HCV NS4 protein is >95% pure as determined by 10% PAGE (coomassie staining). Source
Phycical Appearance Shipping Condition Shipped with Ice Packs.
Stability HCV NS4 although stable at 4°C for 1 week, should be stored below -18°C .Please prevent freeze thaw cycles.
Formulation 1.5M urea, 25mM Tris-HCl pH-8, 0.2% Triton-X & 50% Glycerol.

Introduction

HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to IFN-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to IFN-based treatment than are the other genotypes (2, 3, 5 and 6).

Purification Method

HCV NS4 protein was purified by proprietary chromatographic technique.

Applications

HCV NS4 antigen is suitable for ELISA and Western blots, excellent antigen for detection of HCV with minimal specificity problems.

Stability

HCV NS4 although stable at 4°C for 1 week, should be stored below -18°C .Please prevent freeze thaw cycles.