Heptadecanoic Acid methyl ester
(Synonyms: 十七烷酸甲酯) 目录号 : GC41548
An esterified form of heptadecanoic acid
Cas No.:1731-92-6
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Heptadecanoic acid methyl ester is an esterified form of heptadecanoic acid . It has been found in biodiesel produced by C. sorokiniana microalgae as well as in several types of animal fat biodiesel. Heptadecanoic acid methyl ester has been used as an internal standard for the quantification of fatty acid methyl esters in human plasma.
| Cas No. | 1731-92-6 | SDF | |
| 别名 | 十七烷酸甲酯 | ||
| Canonical SMILES | O=C(CCCCCCCCCCCCCCCC)OC | ||
| 分子式 | C18H36O2 | 分子量 | 284.5 |
| 溶解度 | DMF: 25 mg/mL,DMF:PBS (pH 7.2)(1:3): 0.25 mg/mL,DMSO: 10 mg/mL,Ethanol: 25 mg/mL | 储存条件 | Store at -20°C |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
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| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 3.5149 mL | 17.5747 mL | 35.1494 mL |
| 5 mM | 0.703 mL | 3.5149 mL | 7.0299 mL |
| 10 mM | 0.3515 mL | 1.7575 mL | 3.5149 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
[Quantifiable method of polyunsaturated fatty acids in human plasma by optimized gas chromatography]
Wei Sheng Yan Jiu 2021 Nov;50(6):981-985.PMID:34949327DOI:10.19813/j.cnki.weishengyanjiu.2021.06.018.
Objective: To optimize the quantifiable method for determining polyunsaturated fatty acids in human plasma by gas chromatography(GC). Methods: Plasma was added with Heptadecanoic Acid methyl ester internal standard, and the total plasma lipids was extracted with methanol and n-hexane under the condition of ultrasonic water bath. The sulfuric acid methanol was used for methyl esterification. After centrifugation, the supernatant was filtered with a membrane and dried by nitrogen, and then re-dissolved by n-hexane. HP-88 GC column(30 m×0.25 mm, 0.2 μm) was used to separate linoleic acid(LA), α-linolenic acid(α-ALA), arachidonic acid(AA) and docosahexaenoic acid(DHA) with programmed temperature, and internal standard method was used to draw standard curve for quantitative analysis. Results: Ultrasonic water bath at 40 ℃ for 20 min could realize a higher total lipid extraction rate in a shorter time. The experimental concentration of four fatty acids range showed a good linear relation with the peak area ratio, correlation coefficient(r>0.995). The rate of recovery of four fatty acids were between 84.05%-101.23% with relative standard deviation(RSD) of 1.21%-6.77%, and the RSD of precision, within-day stability and day to day stability were 0.01%-0.04% and 0.02%-0.07%, respectively. No significant differences in the concentration of α-ALA, AA and DHA were observed between plasma and serum. The concentration(M(P25, P75)) of LA was higher in serum [93.38(79.18, 116.41) μg/mL]compared with plasma [72.12(50.93, 101.13) μg/mL], and the difference were significant(P<0.05). Conclusion: This method has a higher rate of total plasma lipids with shorter time, and the internal standard-standard curve method could eliminate the influence of the sample amount on the result. The determination of four polyunsaturated fatty acids was accurate, which could be used for the determination of plasma polyunsaturated fatty acids content in large sample populations.
Hollow fiber liquid-phase microextraction coupled with gas chromatography-flame ionization detection for the profiling of fatty acids in vegetable oils
J Chromatogr A 2010 Dec 24;1217(52):8073-8.PMID:21081239DOI:10.1016/j.chroma.2010.10.052.
The development of a two phase hollow fiber liquid-phase microextraction technique, followed by gas-chromatography-flame ionization detection (GC-FID) for the profiling of the fatty acids (FAs) (lauric, myristic, palmitic, stearic, palmitoleic, oleic, linoleic, linolenic and arachidic) in vegetable oils is described. Heptadecanoic Acid methyl ester was used as the internal standard. The FAs were transesterified to their corresponding methyl esters prior to the extraction. Extraction parameters such as type of extracting solvent, temperature, extraction time, stirring speed and salt addition were studied and optimized. Recommended conditions were extraction solvent, n-tridecane; extraction time, 35 min; extraction temperature, ambient; without addition of salt. Enrichment factors varying from 37 to 115 were achieved. Calibration curves for the nine FAs were well correlated (r(2)>0.994) within the range of 10-5000 μg L(-1). The limit of detection (signal:noise, 3) was 4.73-13.21 ng L(-1). The method was successfully applied to the profiling of the FAs in palm oils (crude, olein, kernel, and carotino cooking oil) and other vegetable oils (soybean, olive, coconut, rice bran and pumpkin). The encouraging enrichments achieved offer an interesting option for the profiling of the minor and major FAs in palm and other vegetable oils.