Heptadecanoyl-L-carnitine (chloride)
(Synonyms: CAR 17:0, C17:0 Carnitine, L-Carnitine heptadecanoyl ester, L-Heptadecanoylcarnitine) 目录号 : GC52219
A long-chain acylcarnitine
Cas No.:173686-69-6
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
Quality Control & SDS
- View current batch:
- Purity: >95.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Heptadecanoyl-L-carnitine is a long-chain acylcarnitine composed of heptadecanoic acid and L-carnitine . Levels of heptadecanoyl-L-carnitine are increased in dried blood spots from neonates with propionic or methylmalonic acidemias, inborn errors of metabolism characterized by a deficiency in the activity of propionyl-CoA carboxylase or L-methylmalonyl-CoA mutase or its cofactor 5-deoxyadenosylcobalamin, respectively.1
1.Malvagia, S., Haynes, C.A., Grisotto, L., et al.Heptadecanoylcarnitine (C17) a novel candidate biomarker for propionic and methylmalonic acidemias during expanded newborn screeningClin. Chim. Acta450342-348(2015)
| 制备储备液 | |||
 |
1 mg | 5 mg | 10 mg |
| 1 mM | 2.2217 mL | 11.1086 mL | 22.2173 mL |
| 5 mM | 0.4443 mL | 2.2217 mL | 4.4435 mL |
| 10 mM | 0.2222 mL | 1.1109 mL | 2.2217 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。