Histone H3K9Me2 (3-17) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)
(Synonyms: Histone H3 (3-17) (Lys9me2), H-Thr-Lys-Gln-Thr-Ala-Arg-Lys(Me2)-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-OH, Lys(Me2)9-Histone H3 (3-17), TKQTAR-K(Me2)-STGGKAPR) 目录号 : GC90308一段组成蛋白质的小分子,来自于组蛋白H3。
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
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- Purity: >95.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Histone H3K9Me2 (3-17) is a peptide fragment of histone H3 that corresponds to amino acid residues 4-18 of the human histone H3 sequence. Dimetlation of histone H3 at lysine 9 is associated with transcriptional repression.1 Heterochromatin protein 1-α (HP1-α), HP1-β, and HP1-γ selectively bind histone H3 N-terminal peptides containing dimetlated lysine 9 over unmodified lysine 9.2 In mouse embryos, maternal chromatin containing H3K9Me2 is bound by PGC7, which preserves DNA metlation and protects 5-metlcytosine from conversion to 5-droxymetlcytosine.3
制备储备液 | |||
1 mg | 5 mg | 10 mg | |
1 mM | 0.6192 mL | 3.0962 mL | 6.1923 mL |
5 mM | 0.1238 mL | 0.6192 mL | 1.2385 mL |
10 mM | 0.0619 mL | 0.3096 mL | 0.6192 mL |
第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量) | ||||||||||
给药剂量 | mg/kg | 动物平均体重 | g | 每只动物给药体积 | ul | 动物数量 | 只 | |||
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方) | ||||||||||
% DMSO % % Tween 80 % saline | ||||||||||
计算重置 |
计算结果:
工作液浓度: mg/ml;
DMSO母液配制方法: mg 药物溶于 μL DMSO溶液(母液浓度 mg/mL,
体内配方配制方法:取 μL DMSO母液,加入 μL PEG300,混匀澄清后加入μL Tween 80,混匀澄清后加入 μL saline,混匀澄清。
1. 首先保证母液是澄清的;
2.
一定要按照顺序依次将溶剂加入,进行下一步操作之前必须保证上一步操作得到的是澄清的溶液,可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。