HMGA2 Human
目录号 : GP23656High Mobility Group AT-Hook 2 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 80.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | High Mobility Group AT-Hook 2; HMGIC; High-Mobility Group(Nonhistone Chromosomal) Protein Isoform I-C; High Mobility Group AT-HookProtein; BABL; HMGI-C; LIPO; STQTL9; High Mobility Group Protein HMGI-C;HMGA2. | ||
| Amino Acid Sequence | MSARGEGAGQ PSTSAQGQPA APAPQKRGRG RPRKQQQEPT GEPSPKRPRG RPKGSKNKSP SKAAQKKAEA TGEKRPRGRP RKWPQQVVQK KPAQEETEET SSQESAEEDL EHHHHHH. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | HMGA2 protein solution (0.25mg/ml) containing 20mMTris-HCl buffer (pH 8.0), 0.2M NaCl, 50% glycerol, 2mM DTT and 250mM Imidazole. | ||
High Mobility Group AT-Hook 2 (HMGA2) is a member of the non-histone chromosomal high mobility group (HMG) family. HMG proteins perform as architectural factors and are necessary components of the enhancesome. This protein contains structural DNA-binding domains and may function as a transcriptional regulating factor. In addition, identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma proposes a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is implicated in diet-induced obesit. Among the Diseases associated with HMGA2 are diffuse lipomatosis, and 12q14 microdeletion syndrome.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.