HMGN3 Human
目录号 : GP23662High Mobility Group Nucleosomal Binding Domain 3 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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HMGN3 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 100 amino acids (1-77 a.a) andhaving a molecular mass of 10.8 kDa.HMGN3 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.
| Purity | Greater than 95% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | High Mobility Group Nucleosomal Binding Domain 3; TRIP7;TR-Interacting Protein 7; High Mobility Group Nucleosome-BindingDomain-Containing Protein 3; Thyroid Hormone Receptor Interacting Protein 7; ThyroidReceptor-Interacting Protein 7; Thyroid Hormone Receptor Interactor 7; PNAS-24;PNAS-25; TRIP-7; High mobility group nucleosome-binding domain-containingprotein 3. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMPKRKSP ENTEGKDGSK VTKQEPTRRS ARLSAKPAPP KPEPKPRKTSAKKEPGAKIS RGAKGKKEEK QEAGKEGTEN. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. | ||
| Formulation | HMGN3 protein solution (0.5mg/ml) containing 20mMTris-HCl buffer (pH7.0) and 10% glycerol. | ||
High Mobility Group Nucleosomal Binding Domain 3 (HMGN3), binds thyroidhormone receptor beta, however it occurs only in the presence of thyroidhormone. Thyroid hormone receptors are hormone-dependent transcription factorswhich regulate expression of a variety of particular target genes. HMGN3 is considered to reduce the compactnessof the chromatin fiber in nucleosomes, in that way enhancing transcription fromchromatin templates.
Store at 4°C if entire vial will be used within 2-4 weeks.