HNRNPAB Human
目录号 : GP23666Heterogeneous Nuclear Ribonucleoprotein A/B Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 95.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Heterogeneous Nuclear Ribonucleoprotein A/B; ABBP-1; ABBP1;APOBEC1-Binding Protein 1; HnRNP A/B; Apobec-1 Binding Protein 1; ApolipoproteinB MRNA Editing Enzyme; Catalytic Polypeptide 1-Binding Protein 1; HnRNP TypeA/B Protein. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMSEAGEE QPMETTGATE NGHEAVPEGE SPAGAGTGAA AGAGGATAAP PSGNQNGAEGDQINASKNEE DAGKMFVGGL SWDTSKKDLK DYFTKFGEVV DCTIKMDPNT GRSRGFGFIL FKDAASVEKVLDQKEHRLDG RVIDPKKAMA MKKDPVKKIF VGGLNPEATE EKIREYFGEF GEIEAIELPM DPKLNKRRGF VFITFKEEEPVKKVLEKKFH TVSGSKCEIK VAQPKEVYQQ QQYGSGGRGN RNRGNRGSGG GGGGGGQGST NYGKSQRRGGHQNNYKPY | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | HNRNPABprotein solution (0.25mg/ml) containing 30% glycerol and 1mM DTT. | ||
Heterogeneous Nuclear Ribonucleoprotein A/B(HNRNPAB) is a member of the subfamily of ubiquitously expressed heterogeneousnuclear ribonucleoproteins(hnRNPs). The hnRNPs are produced by RNA polymerase II and are components oftheheterogeneous nuclear RNA (hnRNA) complexes. They are linked with pre-mRNAsin the nucleus and seem to influence pre-mRNA processing and further aspects ofmRNA metabolism and transport. Whereas all of the hnRNPs are present in the nucleus, some seem toshuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinctnucleic acid binding properties. HNRNPAB, which binds to one of the componentsof the multiprotein editosomecomplex, has two repeats of quasi-RRM (RNA recognition motif) domains that bindto RNAs. Among the diseases associated with HNRNPABare wells syndrome, and cystic fibrosis.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.