HTLV-1 p24
目录号 : GP25433HTLV-1 p24 Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Protein is >95% pure as determined by 12% SDS-PAGE (coomassie staining). | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Stability | HTLV-1 p24 although stable at 4°C for 1 week, should be stored below -18°C .Please prevent freeze thaw cycles. | ||
| Formulation | HTLV-1 p24 protein solution containing PBS, pH-7.4. | ||
Human T-lymphotropic virus (HTLV) is a human, single-stranded RNA retrovirus that causesT-cell leukemia and T-cell lymphoma. The virus activates a subset of T-helper cellscalled Th1cells. The result is a proliferation of Th1 cells and overproduction of Th1 related cytokines (mainly IFN-gamma and TNF-alpha). Feedback mechanisms of these cytokines cause a suppression of the Th2 lymphocytes and a reduction of Th2 cytokine production (mainly IL-4, IL-5, IL-10 and IL-13). The end result is a reduction in the ability of the infected host to mount an adequate immune response to invading organisms that require a predominantly Th2 dependant response (these include parasitic infections and production of mucosal and humoral antibodies). HTLV-1 p24 is usually used for clinical diagnosis and forms both monomer and dimer on SDS-PAGE gel but the majority of protein is a dimer.
HTLV-1 p24 although stable at 4°C for 1 week, should be stored below -18°C .Please prevent freeze thaw cycles.