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IBSP Human

目录号 : GP23682

Integrin Binding Sialoprotein ,Human Recombinant

IBSP Human Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-10工作日
10μg
¥2,030.00
5-10工作日
1mg
¥72,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

Description

IBSP produced in Sf9 Baculovirus cells is a single,glycosylated polypeptide chain containing 309 amino acids (17-317aa) and havinga molecular mass of 34.5kDa (Migrates at 70-100kDa on SDS-PAGE under reducingconditions).

Product Data

Purity Greaterthan 90.0% as determined by SDS-PAGE. Source Sf9,Baculovirus cells.
Phycical Appearance Sterile Filtered colorless solution. Shipping Condition Shipped with Ice Packs.
Synonyms Integrin Binding Sialoprotein; Integrin-Binding Sialoprotein;Bone Sialoprotein II; Cell-Binding Sialoprotein; BSP II ; BNSP; BoneSialoprotein; BSP-II; SP-II; BSP.
Amino Acid Sequence FSMKNLHRRV KIEDSEENGV FKYRPRYYLY KHAYFYPHLK RFPVQGSSDSSEENGDDSSE EEEEEEETSN EGENNEESNE DEDSEAENTT LSATTLGYGE DATPGTGYTG LAAIQLPKKAGDITNKATKE KESDEEEEEE EEGNENEESE AEVDENEQGI NGTSTNSTEA ENGNGSSGGD NGEEGEEESVTGANAEDTTE TGRQGKGTSK TTTSPNGGFE PTTPPQVYRT TSPPFGKTTT VEYEGEYEYT GANEYDNGYEIYESENGEPR GDNYRAYEDE YSYFKGQGYD GYDGQNYYHH QLEHHHHHH.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation IBSP protein solution (0.5mg/ml) contains PhosphateBuffered Saline (pH 7.4), 10% glycerol and 0.1mM PMSF.

Introduction

IntegrinBinding Sialoprotein (IBSP) is a monomeric noncollagenous protein which belongsto the SIBLING family of extracellular matrix (ECM) proteins. IBSP issynthesized by platelets, odontoblasts, osteocytes, osteoblasts, osteoclasts,and bone marrow stromal cells. IBSP forms an integral part of the mineralizedmatrix and also plays a role as the main mediator of the hypertrophicchondrocytes-induced angiogenesis. IBSP which binds firmly to hydroxyapatite isrelated to the severity of histological cartilage lesions.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

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