IFN a 2b Human, 20 kd PEG
目录号 : GP20387Interferon-alpha 2b 20kd-Pegylated Human Recombinant
Sample solution is provided at 25 µL, 10mM.
Interferon-a 2b Human Recombinant produced in E.coli is a single, non-glycosylated, polypeptide chain containing 165 amino acids and having a molecular mass of 19269 Dalton. The PegylatedIFN-a 2b is produced by attaching a 20kDa mPEG-aldehyde to the N-terminal IFN alpha-2b. Interferon-a 2b is purified by proprietary chromatographic techniques.
Purity | Greater than 97.0% as determined by SEC-HPLC. | Source | Escherichia Coli. |
Phycical Appearance | Colorless, clear and transparent solution. | Shipping Condition | Shipped with Ice Packs. |
Synonyms | Interferon alpha 2b; IFNA; INFA2; MGC125764; MGC125765. | ||
Stability | IFN alpha-2b PEG should be stored refrigerated at 2бу to 8°C . Vials should be kept in theirpackaging to protect from light until the time of use. Shaking and freezing should be avoided. | ||
Biological Activity | The specific activity as determined in a viral resistance assay using VSV-WISH cells was found to be 3,000,000 IU/mg. | ||
Formulation | IFN-a 2b is supplied in solution (1.48mg/ml)containing 20mM Acetate Buffer (pH 6.0), 0.8%NaCl and 0.005% Polysorbate 80. |
IFN-alpha is produced by macrophages and has antiviral activities. Interferon stimulates the production of two enzymes: protein kinase and an oligoadenylate synthetase.
The specific activity as determined in a viral resistance assay using VSV-WISH cells was found to be 3,000,000 IU/mg.
IFN alpha-2b PEG should be stored refrigerated at 2бу to 8°C . Vials should be kept in theirpackaging to protect from light until the time of use. Shaking and freezing should be avoided.