IGF2 Mouse
目录号 : GP26036IGF2 Mouse Recombinant produced in E
Sample solution is provided at 25 µL, 10mM.
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IGF2 Mouse Recombinant produced in E.Coli is a single, non-glycosylated, monomeric polypeptide chain containing 67 amino acids and having a total molecular mass of 7.4kDa.The IGF2 is purified by proprietary chromatographic techniques.
| Purity | Greater than 95.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | Shipping Condition | atRoomtemp. |
| Synonyms | Somatomedin-A, IGF2, INSIGF, pp9974, C11orf43, FLJ22066, FLJ44734 | ||
| Amino Acid Sequence | AYGPGETLCG GELVDTLQFV CSDRGFYFSR PSSRANRRSR GIVEECCFRS CDLALLETYC ATPAKSE | ||
| Solubility | It is recommended to reconstitute the lyophilized IGF2in sterile water at a concentration of 0.1 mg/ml, which can then be further diluted to other aqueous solutions. | ||
| Stability | LyophilizedIGF2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitutionIGF2 Human should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | ||
| Biological Activity | The ED50 as determined by FDC-P1 cell proliferation is ≤ 50 ng/mL, corresponding to a specific activity of ≥ 2.0 x 10^4 units/mg. | ||
| Formulation | Lyophilized from a sterile (0.2µ) filtered solution containing 0.1 % trifluoroacetic acid (TFA). | ||
Insulin-like growth factor II (IGF-II) is an important foetal growth hormone.IGF-II is made by theca cells during gestation. IGF-II binds the sink IGF-II receptor (IGF2R) which results in IGF-II degradation.IGF-II also engages the IGF-I receptor (IGF1R) to arbitrate embryonic growth.
The ED50 as determined by FDC-P1 cell proliferation is ≤ 50 ng/mL, corresponding to a specific activity of ≥ 2.0 x 10^4 units/mg.
LyophilizedIGF2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitutionIGF2 Human should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.