IgM Human
目录号 : GP26299Human Immunoglobulin-M produced in human plasma having a molecular mass of 950kDa
Sample solution is provided at 25 µL, 10mM.
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Human Immunoglobulin-M produced in human plasma having a molecular mass of 950kDa.
| Purity | Greater than 95.0%. | Source | Human plasma. |
| Phycical Appearance | Sterile Filtered solution. | Shipping Condition | withIcePacks |
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | IgM solution (1.98mg/ml) contains 50mM TRIS buffer, pH 8.0, 0.2M NaCl and 0.05% NaN3. | ||
Immunoglobulin M (IgM) is a basic antibody produced by B cells. IgM is the first antibody to emerge in response to initial exposure to an antigen. IgM antibodies are found in the blood and lymph fluid and are the third most widespread serum Ig. Immunoglobulin M (IgM), being the 3rd most widespread serum Ig and exists in two forms- mostly as a pentamer (970kDa) but also as a hexamer. The pentameric IgM has 10 binding sites since each monomer has two antigen binding sites. Due to distance constraints in the hexameric complex, the J chain is found in pentameric IgM but not in the hexameric form. IgM antibodies, which appear early in the course of an infection, typically reappear to a smaller extent after additional exposure. IgM, as opposed to IgG antibodies, do not pass across the human placenta. These properties of IgM make it suitable for the diagnosis of infectious diseases.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.