IL 22 Human
目录号 : GP20620Interleukin-22 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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Interleukin-22 Human Recombinant produced in E.Coli is a single, non-glycosylated homodimeric polypeptide chain containing 2 x 146 amino acids and having a total molecular mass of 33,607 Dalton. The IL-22 is purified by proprietary chromatographic techniques.
| Purity | Greater than 97.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | Shipping Condition | Shipped at Room temp. |
| Synonyms | IL-TIF; TIFa; IL-10-related T-cell-derived-inducible factor; IL-22; ILTIF; IL-D110; zcyto18; MGC79382; MGC79384; TIFIL-23. | ||
| Amino Acid Sequence | The sequence of the first five N-terminal amino acids was determined and was found to be Met-Ala-Pro-Ile-Ser. | ||
| Solubility | It is recommended to reconstitute the lyophilized Interleukin -22 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. | ||
| Stability | Lyophilized Interleukin-22 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution IL22 should be stored at 4°C between 2-7 days and for future use below -18°C .Please prevent freeze-thaw cycles. | ||
| Biological Activity | The Biological Activity was determined by the ability to activiate STAT following receptor ligand interaction. | ||
| Formulation | Each mg contains 50mM Phosphate buffer pH=7.1. | ||
IL-22 is a member of the IL-10 family of regulatory cytokines.Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes, IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas. IL-22 signals through a receptor system consisting of IL-10R-beta/CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family.
The Biological Activity was determined by the ability to activiate STAT following receptor ligand interaction.
Lyophilized Interleukin-22 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution IL22 should be stored at 4°C between 2-7 days and for future use below -18°C .Please prevent freeze-thaw cycles.