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IL 3 Dog

目录号 : GP20493

Interleukin-3 Canine Recombinant

IL 3 Dog Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-10工作日
10μg
¥2,030.00
5-10工作日
1mg
¥37,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

Quality Control & SDS

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产品描述

Interleukin-3 Canine Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 120 amino acids and having a molecular mass of 14 kDa.The IL-3 is purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 97.0% as determined by:(a) Analysis by HPLC. (b) Analysis by SDS-PAGE. Source Escherichia Coli.
Phycical Appearance Sterile Filtered White lyophilized (freeze-dried) powder. Shipping Condition Shipped at Room temp.
Synonyms MCGF (Mast cell growth factor); Multi-CSF; HCGF; P-cell stimulation factor; IL-3; MGC79398; MGC79399.
Amino Acid Sequence RPFSTDLPKQ YFTMINEIME MLNKSPSPSE EPLDSNEKET LLEDTLLRPN LDVFLNASSK FHKNGLLIWN NLKEFLPLLP TPTPRGEPIS IMENNWGDFQ RKLKKYLEAL DNFLNFKNKP.
Solubility It is recommended to reconstitute the lyophilized IL3 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Stability Lyophilized IL3 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution IL3 should be stored at 4°C between 2-7 days and for future use below -18°C .Please prevent freeze-thaw cycles.
Biological Activity The ED50 as determined by the dose-dependant stimulation of TF-1 cells is < 0.2 ng/ml, corresponding to a Specific Activity of 5,000,000 IU/mg.
Formulation Lyophilized from a concentrated (1mg/ml) solution in water containing 1X PBS pH7.4.

Introduction

IL3 is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.

Biological Activity

The ED50 as determined by the dose-dependant stimulation of TF-1 cells is < 0.2 ng/ml, corresponding to a Specific Activity of 5,000,000 IU/mg.

Stability

Lyophilized IL3 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution IL3 should be stored at 4°C between 2-7 days and for future use below -18°C .Please prevent freeze-thaw cycles.