IL 6 Rat
目录号 : GP20521Interleukin-6 Rat Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 90.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | Shipping Condition | Shipped at Room temp. |
| Synonyms | IFN-b2; B cell differentiation factor (BCDF); BSF-2; HPGF; HSF; MGI-2; IL-6; Interleukin HP-1; B-cell hybridoma growth factor. | ||
| Amino Acid Sequence | The sequence of the first five N-terminal amino acids was determined and was found to be Met-Phe-Pro-Thr-Ser. | ||
| Solubility | It is recommended to reconstitute the lyophilized Interleukin-6 with 10mM HCl at a concentration of 0.1 mg/ml which can then be further diluted to other aqueous solutions. | ||
| Stability | Lyophilized Interleukin-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution IL6 should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. | ||
| Biological Activity | The ED50 is less than 0.01 ng/ml as determined by dose-dependent stimulation of mouse 7TD1 cells. | ||
| Formulation | The protein was lyophilized from 0.02% TFA. | ||
Interleukin-6 is a potent pro-inflammatory cytokine primarily produced by activated T cells and an assortment of other cells including endothelial cells and macrophages. IL-6 affects B and T lymphocytes and has been shown to have a role in host defense, acute phase reactions, immune responses and hematopoiesis.
The ED50 is less than 0.01 ng/ml as determined by dose-dependent stimulation of mouse 7TD1 cells.
Lyophilized Interleukin-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution IL6 should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.