IL15RA Human
目录号 : GP20574Interleukin 15 Receptor Alpha, Recombinant Human
Sample solution is provided at 25 µL, 10mM.
Purity | Greater than 90.0% as determined by SDS-PAGE. | Source | Sf9, Baculovirus cells. |
Phycical Appearance | Sterile filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
Synonyms | Interleukin 15 Receptor Subunit Alpha; Interleukin 15 Receptor; Alpha; Interleukin 15 Receptor Alpha Isoform EM2; Interleukin 15 Receptor Alpha Isoform IC2; Interleukin 15 Receptor Alpha Isoform IC3; Interleukin 15 Receptor Alpha Isoform IC4; Interleukin 15 Receptor Alpha Isoform IC5; Interleukin 15 Receptor Alpha Isoform IC6; Interleukin 15 Receptor Alpha Isoform IC7;Interleukin 15 Receptor Alpha Isoform IC8; Interleukin-15 Receptor Subunit Alpha; IL-15 Receptor Subunit Alpha; CD215 Antigen; IL-15R-Alpha; IL-15RA; CD215. | ||
Amino Acid Sequence | ADPITCPPPM SVEHADIWVK SYSLYSRERY ICNSGFKRKA GTSSLTECVL NKATNVAHWT TPSLKCIRDP ALVHQRPAPP STVTTAGVTP QPESLSPSGK EPAASSPSSN NTAATTAAIV PGSQLMPSKS PSTGTTEISS HESSHGTPSQ TTAKNWELTA SASHQPPGVY PQGHSDTTLEPKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRD ELTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPPVLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG KHHHHHH | ||
Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
Biological Activity | Determined by its ability to inhibit proliferation using CTLL2 mouse cytotoxic T cells. The ED50 for this effect is < 2 ng/ml with Human IL-15. | ||
Formulation | IL15RA protein solution (0.5mg/ml) contains Phosphate buffered saline (pH7.4) and 10% glycerol. |
IL15RA, also known as Interleukin 15 Receptor Alpha, is a high-affinity receptor for interleukin-15. IL15RA plays a role as a heterotrimer with the IL-2 receptor beta and gamma subunits to commence signal transduction. IL15/IL15R alpha complexes can transmit reverse signaling which promotes cellular adhesion, tyrosine phosphorylation of intracellular proteins, as well as cytokine secretion by the IL?15/IL15R alpha expressing cells.
Determined by its ability to inhibit proliferation using CTLL2 mouse cytotoxic T cells. The ED50 for this effect is < 2 ng/ml with Human IL-15.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.