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IL21R Human

目录号 : GP20619

Interleukin-21 Receptor Human Recombinant

IL21R Human Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-10工作日
10μg
¥2,030.00
5-10工作日
1mg
¥72,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

IL21R produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain (20-232 a.a.) and fused to an 8 aa His Tag at C-terminus containing a total of 221 amino acids and having a molecular mass of 25.6kDa.IL21R shows multiple bands between 28-40kDa on SDS-PAGE, reducing conditions and purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 90.0% as determined by SDS-PAGE. Source Sf9, Baculovirus cells.
Phycical Appearance Sterile filtered colorless solution. Shipping Condition Shipped with Ice Packs.
Synonyms Interleukin 21 Receptor; Novel Interleukin Receptor; IL-21 Receptor; NILR; Interleukin-21 Receptor; CD360 Antigen; IL-21R; CD360.
Amino Acid Sequence CPDLVCYTDY LQTVICILEM WNLHPSTLTL TWQDQYEELK DEATSCSLHR SAHNATHATY TCHMDVFHFM ADDIFSVNIT DQSGNYSQEC GSFLLAESIK PAPPFNVTVT FSGQYNISWR SDYEDPAFYM LKGKLQYELQ YRNRGDPWAV SPRRKLISVD SRSVSLLPLE FRKDSSYELQ VRAGPMPGSS YQGTWSEWSD PVIFQTQSEE LKEVEHHHHH H
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation IL21R protein solution (1mg/ml) contains Phosphate buffered saline (pH7.4) and 10% glycerol.

Introduction

Interleukin-21 receptor, also known as IL21R is a member of the type Icytokine receptors family. IL21R forms a heterodimeric receptor complex withthe common gamma-chain, a receptor subunit which is also shared by thereceptors for interleukin 2, 4, 7, 9, and 15. Furthermore, IL21 receptortransduces the growth promoting signal of IL21, and is significant for theproliferation as well as differentiation of T cells, B cells, and naturalkiller (NK) cells. The ligand binding of IL21 receptor leads to the activationof numerous downstream signaling molecules, including JAK1, JAK3, STAT1, aswell as STAT3.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.