IL36RN Human
目录号 : GP20655Interleukin-36 Receptor Antagonist Human Recombinant
Sample solution is provided at 25 µL, 10mM.
Purity | Greater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. | Source | Escherichia Coli. |
Phycical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | Shipping Condition | Shipped at Room temp. |
Synonyms | Interleukin-36 receptor antagonist protein; FIL1 delta; IL-1-related protein 3; IL-1RP3; Interleukin-1 HY1; IL-1HY1; Interleukin-1 delta; IL-1 delta; Interleukin-1 family member 5; IL-1F5; Interleukin-1 receptor antagonist homolog 1; IL-1ra homolog 1; Interleukin-1-like protein 1; IL-1L1; IL36RN; FIL1D; IL1F5; IL1HY1; IL1L1; IL1RP3; FIL1; PSORP; IL36RA; FIL1(DELTA). | ||
Amino Acid Sequence | The sequence of the first five N-terminal amino acids was determined and was found to be Met-Val-Leu-Ser-Gly. | ||
Solubility | It is recommended to quick spin followed by reconstitution of IL1F5 in PBS to a concentration no less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | ||
Stability | Lyophilized IL1F5 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution IL1F5 should be stored at 4°C between 2-7 days and for future use below -18°C .Please prevent freeze-thaw cycles. | ||
Biological Activity | As measured by its binding ability in a functional ELISA, immobilized IL1F5at 1 µg/ml (100 ?l/well) can bind rHuIL-1 Rrp2/Fc Chimera with a linear range of 0.15- 5 µg/ml. | ||
Formulation | IL1F5 was lyophilized after extensive dialysis against 20mM Phosphate buffer, pH7.4. |
Human interleukin family 1, member 5 (IL-1F5 / FIL1-delta) belongs to the interleukin 1 cytokine family. IL1F5 is expressed by a variety of cells including monocytes, Bcells, dendritic cells/Langerhans cells, keratinocytes,and gastric fundus Parietal and Chief cells. IL1F5 is an antagonist of IL1F9; however IL1F5 activity related to receptor binding remains unclear. Human and mouse IL1F5 share 90% amino acid sequence identity.
As measured by its binding ability in a functional ELISA, immobilized IL1F5at 1 µg/ml (100 ?l/well) can bind rHuIL-1 Rrp2/Fc Chimera with a linear range of 0.15- 5 µg/ml.
Lyophilized IL1F5 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution IL1F5 should be stored at 4°C between 2-7 days and for future use below -18°C .Please prevent freeze-thaw cycles.