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IMPAD1 Mouse Bioactive

目录号 : GP23702

Inositol Monophosphatase Domain Containing 1 Mouse Recombinant Bioactive

IMPAD1 Mouse Bioactive Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-10工作日
10μg
¥2,030.00
5-10工作日
100μg
¥16,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

Description

IMPAD1 Mouse Recombinant produced in Sf9 Baculoviruscells is a single, glycosylated polypeptide chain containing 332 amino acids (34-356a.a.)and having a molecular mass of 36.2kDa. (Molecular size on SDS-PAGE will appearat approximately 28-40kDa).IMPAD1 is expressed with a6 amino acid His tag at C-Terminus and purified by proprietary chromatographictechniques.

Product Data

Purity Greaterthan 95.0% as determined by SDS-PAGE. Source Sf9,Baculovirus cells.
Phycical Appearance Sterile Filtered colorless solution. Shipping Condition Shipped with Ice Packs.
Synonyms Inositol monophosphatase 3; IMP 3; IMPase 3; Golgi 3-primephosphoadenosine 5-prime phosphate 3-prime phosphatase; Golgi-resident PAPphosphatase; gPAPP; Inositol monophosphatase domain-containing protein 1; Inositol-1(or4)-monophosphatase 3; Myo-inositol monophosphatase A3.
Amino Acid Sequence ADPGRFSLFG LGSEPAAGEAEVASDGGTVD LREMLAVAVL AAERGGDEVR RVRESNVLHE KSKGKTREGA DDKMTSGDVL SNRKMFYLLK TAFPNVQINTEEHVDASDKE VIVWNRKIPE DILKEIAAPK EVPAESVTVW IDPLDATQEY TEDLRKYVTT MVCVAVNGKPVLGVIHKPFSEYTAWAMVDG GSNVKARSSYNEKTPKIIVS RSHAGMVKQV ALQTFGNQTS IIPAGGAGYK VLALLDVPDM TQEKADLYIH VTYIKKWDIC AGNAILKALGGHMTTLNGEE ISYTGSDGIE GGLLASIRMN HQALVRKLPD LEKSGHHHHH HH.
Stability Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Biological Activity Specificactivity is > 5,000 pmol/min/ug and is defined as the amount of enzyme thathydrolyze Adenosine 3, 5-diphosphate per minute at pH 7.5 at 25C.
Formulation IMPAD1 protein solution (0.5mg/ml) containing PhosphateBuffered Saline (pH 7.4) and 10% glycerol.

Introduction

Inositol monophosphatase 3 (IMPAD1) belongs to the inositol monophosphatase family. IMPAD1 is restricted to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). IMPAD1 gene mutations cause the GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of the IMPAD1 gene is located on the long arm of chromosome 1.

Biological Activity

Specificactivity is > 5,000 pmol/min/ug and is defined as the amount of enzyme thathydrolyze Adenosine 3, 5-diphosphate per minute at pH 7.5 at 25C.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

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