ING1 Human
目录号 : GP23706Inhibitor of Growth Family, Member 1 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
Purity | Greater than 90.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
Synonyms | Inhibitor Of Growth Family; Member 1; Growth Inhibitory Protein ING1; Tumor Suppressor ING1; Growth Inhibitor ING1; Inhibitor Of Growth Protein 1; Inhibitor Of Growth 1; P24ING1c;P33ING1b; P47ING1a; P33ING1; P33; P47; ING1 . | ||
Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMLSPANG EQLHLVNYVE DYLDSIESLP FDLQRNVSLM REIDAKYQEI LKELDECYER FSRETDGAQK RRMLHCVQRA LIRSQELGDE KIQIVSQMVE LVENRTRQVD SHVELFEAQQ ELGDTAGNSG KAGADRPKGE AAAQADKPNS KRSRRQRNNE NRENASSNHD HDDGASGTPK EKKAKTSKKK KRSKAKAERE ASPADLPIDP NEPTYCLCNQ VSYGEMIGCD NDECPIEWFH FSCVGLNHKP KGKWYCPKCR GENEKTMDKA LEKSKKERAY NR. | ||
Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
Formulation | ING1 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0) and 10% glycerol. |
Inhibitor of Growth Family Member 1, also known as ING1 is a tumorsuppressor protein which is able to induce cell growth arrest and apoptosis. ING1is a nuclear protein which physically act together with the tumor suppressorprotein TP53 and is a component of the p53 signaling pathway. In addition, Reducedexpression and rearrangement of ING1 have been identified in various cancers.Multiple alternatively spliced transcript variants encoding distinct isoformshave been described for ING1.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.