Isopropyl myristate
(Synonyms: 十四酸异丙酯) 目录号 : GC60952Isopropyl myristate (IPM) is used as a substitute for natural oils in cosmetics and a co-solvent with skin penetration enhancement properties of active ingredients in many topical and transdermal preparations. Isopropyl myristate is a novel pediculicide rinse (50%) and a safe and effective therapy for the treatment of head lice in children and adults.
Cas No.:110-27-0
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
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- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Isopropyl myristate (IPM) is used as a substitute for natural oils in cosmetics and a co-solvent with skin penetration enhancement properties of active ingredients in many topical and transdermal preparations. Isopropyl myristate is a novel pediculicide rinse (50%) and a safe and effective therapy for the treatment of head lice in children and adults.
[1] Vadgama RN, et al. Biotechnol Rep (Amst). 2015 Oct 24;8:133-137. [2] Kaul N, et al. J Cutan Med Surg. 2007 Sep-Oct;11(5):161-7.
制备储备液 | |||
1 mg | 5 mg | 10 mg | |
1 mM | 3.6975 mL | 18.4877 mL | 36.9754 mL |
5 mM | 0.7395 mL | 3.6975 mL | 7.3951 mL |
10 mM | 0.3698 mL | 1.8488 mL | 3.6975 mL |
第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量) | ||||||||||
给药剂量 | mg/kg | 动物平均体重 | g | 每只动物给药体积 | ul | 动物数量 | 只 | |||
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方) | ||||||||||
% DMSO % % Tween 80 % saline | ||||||||||
计算重置 |
计算结果:
工作液浓度: mg/ml;
DMSO母液配制方法: mg 药物溶于 μL DMSO溶液(母液浓度 mg/mL,
体内配方配制方法:取 μL DMSO母液,加入 μL PEG300,混匀澄清后加入μL Tween 80,混匀澄清后加入 μL saline,混匀澄清。
1. 首先保证母液是澄清的;
2.
一定要按照顺序依次将溶剂加入,进行下一步操作之前必须保证上一步操作得到的是澄清的溶液,可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。