JWH 398 N-(5-hydroxypentyl) metabolite-d5

JWH 398 N-(5-hydroxypentyl) metabolite-d₅ contains five deuterium atoms at the 2, 4, 5, 6, and 7 positions. It is intended for use as an internal standard for the quantification of JWH 398 N-(5-hydroxypentyl) metabolite by GC- or LC-mass spectrometry. JWH 398 is a synthetic cannabinoid (CB) that activates both CB₁ and CB₂ receptors (K_i = 2.3 and 2.8 nM, respectively).¹ It has been reported to be an adulterant of herbal products.^2,3 JWH 398 N-(5-hydroxypentyl) metabolite is a potential metabolite of JWH 398. Metabolism of structurally similar compounds leads to monohydroxylation of the N-alkyl chain, detectable in urine.⁴

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