KCNMB3 Human
目录号 : GP23732KCNMB3 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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KCNMB3 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 149 amino acids (82-207 a.a) andhaving a molecular mass of 16.8kDa.KCNMB3 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.
| Purity | Greaterthan 85.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Potassium Channel Subfamily M Regulatory Beta Subunit 3; PotassiumLarge Conductance Calcium-Activated Channel; Subfamily M Beta Member 3; Calcium-ActivatedPotassium Channel; Subfamily M Subunit Beta-3; Charybdotoxin Receptor SubunitBeta-3; Big Potassium Channel Beta Subunit 3; Maxi K Channel Subunit Beta-3; MaxiK Channel Beta-Subunit 3; BK Channel Beta Subunit 3; BKChannel Subunit Beta-3; K(VCA)BETA-3; SLO-BETA-3;BKBETA3; Hbeta3; KCNMB2; KCNMBL; Large Conductance; Voltage And Ca2+ ActivatedPotassium Channel Maxi K Beta 3 Subunit; Calcium-Activated Potassium ChannelRegulatory Subunit; SLOBETA3; Calcium-activated potassium channel subunitbeta-3. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSKPFMLSI QREESTCTAI HTDIMDDWLD CAFTCGVHCH GQGKYPCLQVFVNLSHPGQK ALLHYNEEAV QINPKCFYTP KCHQDRNDLL NSALDIKEFF DHKNGTPFSC FYSPASQSEDVILIKKYDQ. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | KCNMB3protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M UREAand 10% glycerol. | ||
The KCNMB3 belongs to a family of 4 auxiliary beta subunits found in the mammalian genome, which associate with Slo1 alpha subunits and regulate BK channel function. In humans, the KCNMB3 gene is comprised of 4 N-terminal alternative exons which produce 4 functionally distinct beta3 subunits, beta3a-d. Three variants, beta3a-c, display kinetically distinct inactivation behaviors.
Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.