KEMPFPKYPVEP Peptide (bovine, ovine) (trifluoroacetate salt)
目录号 : GC91847KEMPFPKYPVEP Peptide is a peptide fragment of the dairy protein β-casein.
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
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- Purity: >95.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
KEMPFPKYPVEP Peptide is a peptide fragment of the dairy protein β-casein.[1],[2] It can be produced by the protease M from A. oryzae and is found in dairy products fermented by fungi but not bacteria.[1] KEMPFPKYPVEP Peptide (2 mg/kg) increases the levels of dopamine, norepinephrine, and homovanillic acid, but not serotonin, in the frontal cortex of mice. It improves spatial alternation retention in the Y-maze spatial alternation task and increases novel object exploration time in a novel object recognition test in a mouse model of scopolamine-induced amnesia when administered at a dose of 2 mg/kg.
References:
[1].Ano, Y., Kutsukake, T., Sasaki, T., et al.Identification of a novel peptide from β-casein that enhances spatial and object recognition memory in miceJ. Agric. Food Chem.67(29)8160-8167(2019).
[2].Atamer, Z., Post, A.E., Schubert, T., et al.Bovine β-casein: Isolation, properties and functionality. A reviewInt. Dairy J.66115-125(2017).
制备储备液 | |||
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1 mg | 5 mg | 10 mg |
1 mM | 0.6841 mL | 3.4207 mL | 6.8413 mL |
5 mM | 0.1368 mL | 0.6841 mL | 1.3683 mL |
10 mM | 0.0684 mL | 0.3421 mL | 0.6841 mL |
第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量) | ||||||||||
给药剂量 | mg/kg | 动物平均体重 | g | 每只动物给药体积 | ul | 动物数量 | 只 | |||
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方) | ||||||||||
% DMSO % % Tween 80 % saline | ||||||||||
计算重置 |
计算结果:
工作液浓度: mg/ml;
DMSO母液配制方法: mg 药物溶于 μL DMSO溶液(母液浓度 mg/mL,
体内配方配制方法:取 μL DMSO母液,加入 μL PEG300,混匀澄清后加入μL Tween 80,混匀澄清后加入 μL saline,混匀澄清。
1. 首先保证母液是澄清的;
2.
一定要按照顺序依次将溶剂加入,进行下一步操作之前必须保证上一步操作得到的是澄清的溶液,可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。