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KGF Human, HEK

目录号 : GP20680

Keratinocyte Growth Factor Human Recombinant, HEK

KGF Human, HEK Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-10工作日
10μg
¥2,030.00
5-10工作日
100μg
¥15,400.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

Description

KGF Human Recombinant produced in HEK cells is a glycosylated monomer, having a molecular weight range of 17-30kDa due to glycosylation.The KGF is purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 95% as obsereved by SDS-PAGE. Source HEK.
Phycical Appearance Sterile Filtered White lyophilized (freeze-dried) powder. Shipping Condition Shipped at Room temp.
Synonyms HBGF-7; FGF7; FGF-7; KGF.
Solubility It is recommended to reconstitute the lyophilized KGF in sterile water not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Stability Lyophilized KGF although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution KGF should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Biological Activity The specific activity was determined by the dose-dependent stimulation of the proliferation of 4MBr-5 cells (monkey epithelial cell line) and is typically 1.5-7.5ng/ml corresponding to a Specific Activity of 133,334-666,667IU/mg.
Formulation The KGF was lyophilized from 1mg/ml in 1xPBS.

Introduction

KGF is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.

Biological Activity

The specific activity was determined by the dose-dependent stimulation of the proliferation of 4MBr-5 cells (monkey epithelial cell line) and is typically 1.5-7.5ng/ml corresponding to a Specific Activity of 133,334-666,667IU/mg.

Stability

Lyophilized KGF although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution KGF should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

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