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KLK13 Human, sf9

目录号 : GP21853

Kallikrein-13 Human Recombinant, sf9

KLK13 Human, sf9 Chemical Structure

规格 价格 库存 购买数量
1μg
¥840.00
5-10工作日
5μg
¥2,030.00
5-10工作日
50μg
¥16,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

Description

KLK13 produced in Sf9 Baculovirus cells is a single,glycosylated polypeptide chain containing 267 amino acids (17-277a.a.) andhaving a molecular mass of 29.7kDa.(Molecular size on SDS-PAGE will appear atapproximately 28-40kDa).KLK13 is expressed with a 6 amino acid His tag atC-Terminus and purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 90% as determined by SDS-PAGE. Source Sf9,Baculovirus cells.
Phycical Appearance Sterile Filtered colorless solution. Shipping Condition Shipped with Ice Packs.
Synonyms Kallikrein-Related Peptidase 13; KLKL4; Kallikrein-LikeProtein 4; Kallikrein 13; KLK-L4; Kallikrein-Like Gene 4; Kallikrein-13; EC3.4.21.-; EC 3.4.21; Kallikrein-13.
Amino Acid Sequence GGVSQESSKV LNTNGTSGFL PGGYTCFPHS QPWQAALLVQ GRLLCGGVLVHPKWVLTAAH CLKEGLKVYL GKHALGRVEA GEQVREVVHS IPHPEYRRSP THLNHDHDIM LLELQSPVQLTGYIQTLPLS HNNRLTPGTT CRVSGWGTTT SPQVNYPKTL QCANIQLRSD EECRQVYPGKITDNMLCAGT KEGGKDSCEG DSGGPLVCNR TLYGIVSWGD FPCGQPDRPGVYTRVSRYVL WIRETIRKYE TQQQKWLKGP QHHHHHH.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Biological Activity Specific activity is > 8,000 pmol/min/ug. One unitwill hydrolyze 1.0 pmole of BAEE toNa-Benzoyl-L-arginine per minute at pH8.0 at 25C.
Formulation KLK13 protein solution (0.5mg/ml) contains PhosphateBuffered Saline (pH 7.4) and 10% glycerol.

Introduction

Kallikreins are a subgroup of serine proteases having various physiological functions. Many kallikreins are implicated in carcinogenesis and some have potential of becoming novel cancer and other disease biomarkers. Kallikrein-13 (KLK13) is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. KLK13 gene expression is regulated by steroid hormones and may be useful as a marker for breast cancer.

Biological Activity

Specific activity is > 8,000 pmol/min/ug. One unitwill hydrolyze 1.0 pmole of BAEE toNa-Benzoyl-L-arginine per minute at pH8.0 at 25C.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

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