KLK7 Human, sf9
目录号 : GP21846Kallikrein-7 Human Recombinant, sf9
Sample solution is provided at 25 µL, 10mM.
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KLK7 produced in Sf9 Baculovirus cells is a single,glycosylated polypeptide chain containing 190 amino acids (1-181 a.a.) andhaving a molecular mass of 20.9kDa (Migrates at 28-40kDa on SDS-PAGE underreducing conditions).
| Purity | Greaterthan 95.0% as determined by SDS-PAGE. | Source | Sf9,Baculovirus cells. |
| Phycical Appearance | Sterile Filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | KallikreinRelated Peptidase 7; Kallikrein 7 (Chymotryptic; Stratum Corneum); StratumCorneum Chymotryptic Enzyme; Serine Protease 6; PRSS6; SCCE; HK7;Kallikrein-Related Peptidase 7; Signal Protein; EC 3.4.21.117; EC 3.4.21;HSCCE. | ||
| Amino Acid Sequence | ADPMNEYTVH LGSDTLGDRR AQRIKASKSF RHPGYSTQTH VNDLMLVKLNSQARLSSMVK KVRLPSRCEP PGTTCTVSGW GTTTSPDVTF PSDLMCVDVK LISPQDCTKV YKDLLENSMLCAGIPDSKKN ACNGDSGGPL VCRGTLQGLV SWGTFPCGQP NDPGVYTQVC KFTKWINDTM KKHRHHHHHH. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | KLK7 protein solution (0.5mg/ml) contains PhosphateBuffered Saline (pH 7.4) and 10% glycerol. | ||
KLK7 catalyzes the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. KLK7 cleaves insulin B chain at ''6-Leu- -Cys-7'', ''16-Tyr- -Leu-17'', ''25-Phe- -Tyr-26'' and ''26-Tyr--Thr-27''. KLK7 is involved in the activation of precursors to inflammatory cytokines.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.