KLRB1 Human, Sf9
目录号 : GP23757Killer Cell Lectin-Like Receptor Subfamily B, Member 1 Human Recombinant, Sf9
Sample solution is provided at 25 µL, 10mM.
Purity | Greater than 90% as determined by SDS-PAGE. | Source | Sf9, Baculovirus cells. |
Phycical Appearance | Sterile Filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
Synonyms | Killer Cell Lectin Like Receptor B1; Natural Killer Cell Surface Protein P1A; Killer Cell Lectin-Like Receptor Subfamily B; Member 1; C-Type Lectin Domain Family 5 Member B; HNKR-P1A; NKR-P1A; CLEC5B; NKRP1A; Killer Cell Lectin-Like Receptor Subfamily B Member 1; CD161 Antigen; NKR-P1; CD161; NKR. | ||
Amino Acid Sequence | ADPQKSSIEK CSVDIQQSRN KTTERPGLLN CPIYWQQLRE KCLLFSHTVN PWNNSLADCS TKESSLLLIR DKDELIHTQN LIRDKAILFW IGLNFSLSEK NWKWINGSFL NSNDLEIRGD AKENSCISIS QTSVYSEYCS TEIRWICQKE LTPVRNKVYP DSLEPKSCDK THTCPPCPAPELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTVDKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H. | ||
Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
Formulation | KLRB1 protein solution (0.25mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol. |
KLRB1 has an inhibitory role on natural killer (NK) cells cytotoxicity which are lymphocytes who facilitate cytotoxicity and secrete cytokines subsequent to immune stimulation. Some genes of the C-type lectin superfamily, like the rodent NKRP1 family of glycoproteins, are expressed by NK cells and take part in NK cell function regulation. KLRB1 holds an extracellular domain with a few characteristic motifs of C-type lectins, a transmembrane domain, and a cytoplasmic domain. Due to its external C terminus KLRB1 is considered to be a type II membrane protein.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.