Lauroyl-L-carnitine (chloride)
(Synonyms: L-氯化月桂酰肉碱) 目录号 : GC44044
月桂基-l-肉碱是一种天然存在的化合物，属于酰基肉碱家族。
Cas No.:6919-91-1
Sample solution is provided at 25 µL, 10mM.
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Lauryl-l-carnitine is a naturally occurring compound belonging to the acylcarnitine family. It has been reported that it can be used as a biomarker in the diagnosis of carnitine deficiency.
Lauryl-l-carnitine can be used as a standard for the determination of analytes in maize plants by high performance liquid chromatography-triple quadrupole-liquid chromatography-tandem mass spectrometry (LC-MS/MS). Exogenous application of carnitine stimulates fatty acid transport to mitochondria The possible effects of carnitine on lipid transport between cytoplasmic mitochondrial matrix and mitochondrial respiration in maize leaves grown under normal and cold conditions were investigated[1].
Lauryl-l-carnitine can be used as an analytical standard for quantification of analytes in human urine samples by liquid chromatography/electrospray ionization tandem mass spectrometry (LC/ESI-MS/MS) [2].
References:
[1]: Turk H, Erdal S, Dumlupinar R. Exogenous carnitine application augments transport of fatty acids into mitochondria and stimulates mitochondrial respiration in maize seedlings grown under normal and cold conditions. Cryobiology. 2019 Dec;91:97-103. doi: 10.1016/j.cryobiol.2019.10.003. Epub 2019 Oct 4. PMID: 31589831.
[2]: Abe K, Suzuki H, Maekawa M, Shimada M, Yamaguchi H, Mano N. Matrix effect-corrected liquid chromatography/tandem mass-spectrometric method for determining acylcarnitines in human urine. Clin Chim Acta. 2017 May;468:187-194. doi: 10.1016/j.cca.2017.03.001. Epub 2017 Mar 6. PMID: 28274611.
| Cas No. | 6919-91-1 | SDF | |
| 别名 | L-氯化月桂酰肉碱 | ||
| Canonical SMILES | OC(C[C@H](C[N+](C)(C)C)OC(CCCCCCCCCCC)=O)=O.[Cl-] | ||
| 分子式 | C19H38NO4•Cl | 分子量 | 380 |
| 溶解度 | DMSO : 50 mg/mL (131.59 mM; Need ultrasonic) | 储存条件 | Store at -20°C |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
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| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 2.6316 mL | 13.1579 mL | 26.3158 mL |
| 5 mM | 0.5263 mL | 2.6316 mL | 5.2632 mL |
| 10 mM | 0.2632 mL | 1.3158 mL | 2.6316 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet