Leptin Protein
目录号 : GP20685瘦素人类重组
Sample solution is provided at 25 µL, 10mM.
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Leptin Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 146 amino acids and having a molecular mass of 16 kDa.The Leptin is purified by proprietary chromatographic techniques.
| Purity | Greater than 95.0% as determined by:(a) Analysis by SEC-HPLC.(b) Analysis by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | Shipping Condition | Shipped at Room temp. |
| Synonyms | OB Protein; Obesity Protein; OBS; Obesity factor. | ||
| Amino Acid Sequence | The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Val-Pro-Ile-Gln. | ||
| Solubility | The lyophilized Leptin is very soluble in water and most aqueous buffers below and above the isoelectric point. | ||
| Stability | Lyophilized Leptin although stable at room temperature, should be stored desiccated below 0°C . Reconstituted Leptin is best stored refrigerated at 4°C . | ||
| Biological Activity | Biological Activity is evidenced by inducing proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. | ||
| Formulation | The protein was lyophilized from a concentrated (1mg/ml) solution with 0.0045mM NaHCO3. | ||
A 16-kDa peptide hormone secreted from white adipocytes and implicated in the regulation of food intake and energy balance. Leptin provides the key afferent signal from fat cells in the feedback system that controls body fat stores.
Biological Activity is evidenced by inducing proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor.
Lyophilized Leptin although stable at room temperature, should be stored desiccated below 0°C . Reconstituted Leptin is best stored refrigerated at 4°C .