Leptin Receptor Chicken
目录号 : GP20717Leptin Receptor Chicken Recombinant
Sample solution is provided at 25 µL, 10mM.
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Leptin Binding Domain Chicken Recombinant also called Leptin Receptor produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 208 amino acids and having a molecular mass of 24.5 kDa. Chicken Leptin Receptor consists of the cytokine binding domain of leptin receptor amino acids 420-626 of chicken leptin receptor.The Leptin Binding Domain is purified by proprietary chromatographic techniques.
| Purity | Greater than 99.0% as determined by:(a) Analysis by SEC-HPLC.(b) Analysis by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered colorless solution at a concentration of 0.4 mg/ml. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | OB Protein; Obesity Protein; OBS; Obesity factor; Leptin Receptor. | ||
| Amino Acid Sequence | The sequence of the first six N-terminal amino acids was determined and was found to be Ala-Ile-Asp-Val-Asn-IleBiological ActivityBiological Activity is evidenced by high affinity binding of mammalian leptins at 1:1 molar ratio. | ||
| Stability | Sterile solutions at 0.5mg/ml or less are stable at 4°C for several months. | ||
| Formulation | The protein was filter sterilized and stored at 4°C (0.2 to 0.5 mg/ml) solution of Tris-HCl buffer, pH 9.0 with 150mM NaCl. | ||
Leptin Receptor is a part of the gp130 family of cytokine receptors that stimulate gene transcription by activating cytosolic STAT proteins. Leptin Receptor plays a role in the regulation of fat metabolism and in novel hematopoietic pathway that is obligatory for normal lymphopoiesis. Leptin Receptorparticipates in the regulation of counter-regulatory response to hypoglycemia by inhibiting neurons of the parabrachial nucleus.Leptin Receptoraffectsspecifically on T lymphocyte responses.
Sterile solutions at 0.5mg/ml or less are stable at 4°C for several months.