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(Synonyms: 柠檬酸四锂盐,Litarex) 目录号 : GC11127

柠檬酸锂 (Litarex) 四水合物是藤黄果的主要活性成分。

Lithium Citrate Chemical Structure

Cas No.:6080-58-6

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100g
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Sample solution is provided at 25 µL, 10mM.

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产品描述

Lithium Citrate is the active component of Lithium which is a drug used in treatment of psychiatric disease [1].

Lithium Citrate has shown the effects on metabolic and signaling pathways in the brain based on the specific clinical condition and disease model [2]. Lithium Citrate has been reported to use as a mood stabilizer when treating bipolar mood disorders (BD) and reduce the risk of self-harm in BD patient. In addition, Lithium Citrate has been found to be the choice drug in treatment of acute manic episodes. Moreover, Lithium Citrate has been revealed to dissolve uric acid crystals in urine obtained from patients with gout. Besides, Lithium Citrate has been exhibited to have some dose-dependent side-effects. The most of the side-effects of Lithium Citrate is the tendency to inhibit the prostatic acid phosphatase enzyme (PAP), which leading to the accumulation of PAP [1].

References:
[1] Oruch R1, Elderbi MA2, Khattab HA3, Pryme IF4, Lund A5. Lithium: A review of pharmacology, clinical uses, and toxicity. Eur J Pharmacol. 2014 Jun 30. pii: S0014-2999(14)00493-2.
[2] Janson CG1, Assadi M, Francis J, Bilaniuk L, Shera D, Leone P.Lithium citrate for Canavan disease. Pediatr Neurol. 2005 Oct; 33(4):235-43.

Chemical Properties

Cas No. 6080-58-6 SDF
别名 柠檬酸四锂盐,Litarex
化学名 trilithium;2-hydroxypropane-1,2,3-tricarboxylate;tetrahydrate
Canonical SMILES [Li+].[Li+].[Li+].C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.O.O.O.O
分子式 C6H5O7.4H2O.3Li 分子量 281.98
溶解度 ≥ 14.1mg/mL in DMSO with ultrasonic and warming 储存条件 Store at 2-8°C
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 3.5464 mL 17.7318 mL 35.4635 mL
5 mM 0.7093 mL 3.5464 mL 7.0927 mL
10 mM 0.3546 mL 1.7732 mL 3.5464 mL
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