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Lyso-PAF C-18 -d4 Sale

目录号 : GC47588

A neuropeptide with diverse biological activities

Lyso-PAF C-18 -d4 Chemical Structure

规格 价格 库存 购买数量
100 μg
¥361.00
现货
500 μg
¥1,627.00
现货
1 mg
¥2,878.00
现货

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Sample solution is provided at 25 µL, 10mM.

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产品描述

Lyso-PAF C-18-d4 contains four deuterium atoms at the 9, 9', 10, and 10' positions. It is intended for use as an internal standard for the quantification of Lyso-PAF C-18 by GC- or LC-mass spectrometry. Lyso-PAF C-18 can be formed by either the action of PAF-AH on PAF C-18 or by the action of a CoA-independent transacylase on 1-O-octadecyl-2-acyl-glycerophosphocholine.1,2,3 Lyso PAF C-18 is a substrate for either PAF C-18 formation by the remodeling pathway or selective acylation with arachidonic acid by a CoA-independent transacylase.4,5

1.Stafforini, D.M., Prescott, S.M., and McIntyre, T.M.Human plasma platelet-activating factor acetylhydrolaseThe Journal of Biological Chemisty2624223-4230(1987) 2.Uemura, Y., Lee, T., and Snyder, F.A coenzyme A-independent transacylase is linked to the formation of platelet-activating factor (PAF) by generating the lyso-PAF intermediate in the remodeling pathwayThe Journal of Biological Chemisty2668268-8272(1991) 3.Venable, M.E., Nieto, M.L., Schmitt, J.D., et al.Conversion of 1-O-[3H]alkyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine to lyso platelet-activating factor by the CoA-independent transacylase in membrane fractions of human neutrophilsThe Journal of Biological Chemisty26618691-18698(1991) 4.Prescott, S.M., Zimmerman, G.A., and McIntyre, T.M.Platelet-activating factorThe Journal of Biological Chemisty26517381-17384(1990) 5.Venable, M.E., Olson, S.C., Nieto, M.L., et al.Enzymatic studies of lyso platelet-activation factor acylation in human neutrophils and changes upon stimulationThe Journal of Biological Chemisty2687965-7975(1993)

Chemical Properties

Cas No. N/A SDF
Canonical SMILES O=P(OCC[N+](C)(C)C)([O-])OC[C@H](O)COCCCCCCCCC([2H])([2H])C([2H])([2H])CCCCCCCC
分子式 C26H52D4NO6P 分子量 513.7
溶解度 DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): 10 mg/ml,Water: 20 mg/ml 储存条件 Store at -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
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溶解性数据

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1 mg 5 mg 10 mg
1 mM 1.9467 mL 9.7333 mL 19.4666 mL
5 mM 0.3893 mL 1.9467 mL 3.8933 mL
10 mM 0.1947 mL 0.9733 mL 1.9467 mL
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