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LYVE1 Human

目录号 : GP22541

Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 Human Recombinant

LYVE1 Human Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-10工作日
10μg
¥2,030.00
5-10工作日
1mg
¥72,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

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产品描述

Soluble LYVE1 Human Recombinant fused to a C-terminal His-tag (6xHis) produced in baculovirus is a monomeric, glycosylated, polypeptide containing 232 amino acids (Met-1 to Gly 232) and having a total molecular mass of 25 kDa but as a result of glycosilation the Mw is 40 kDa. The LYVE-1 is purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 95.0% as determined by(a)Analysis by RP-HPLC.(b)Analysis by SDS-PAGE. Source Insect Cells.
Phycical Appearance Sterile Filtered White lyophilized (freeze-dried) powder. Shipping Condition Shipped at Room temp.
Synonyms Lymphatic vessel endothelial hyaluronic acid receptor 1 precursor; LYVE-1; Cell surface retention sequence-binding protein 1; CRSBP-1; Hyaluronic acid receptor; Extracellular link domain-containing protein 1.
Solubility It is recommended to reconstitute the lyophilized LYVE1 in sterile water not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Stability Lyophilized sLYVE-1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution sLYVE-1 should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Formulation LYVE1 was lyophilized from a concentrated (1 mg/ml) sterile solution containing no additives.

Introduction

LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.

Stability

Lyophilized sLYVE-1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution sLYVE-1 should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.