MAP2K6 Human
目录号 : GP22546Mitogen-Activated Protein Kinase Kinase 6 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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MAP2K6 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 283 amino acids (53-314 a.a) andhaving a molecular mass of 32kDa.MAP2K6 is fused to a 21 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.
| Purity | Greater than 85.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Mitogen-Activated Protein Kinase Kinase 6; PRKMK6; MEK6;MKK6; Stress-Activated Protein Kinase Kinase 3;MAPK/ERK Kinase 6; SAPK Kinase3; EC 2.7.12.2; MAPKK; SAPKK; SAPKK3; MEK 6; Protein Kinase; Mitogen-Activated;Kinase 6 (MAP Kinase Kinase 6); Dual Specificity Mitogen-Activated ProteinKinase Kinase 6; Kinase 6 (MAP Kinase Kinase 6); MAP Kinase Kinase6;Mitogen-Activated; Protein Kinase; SKK3. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MLEPIMELGR GAYGVVEKMR HVPSGQIMAV KRIRATVNSQ EQKRLLMDLD ISMRTVDCPFTVTFYGALFR EGDVWICMEL MDTSLDKFYK QVIDKGQTIP EDILGKIAVS IVKALEHLHS KLSVIHRDVKPSNVLINALG QVKMCDFGIS GYLVDEVAKE IDAGCKPYMA PERINPELNQ KGYSVKSDIW SLGITMIELAILRFPYDSWG TPFQQLKQVV EEPSPQLPAD KFSAEFVDFT SQCLKKNSKE RPTYPELMQH PFF. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | MAP2K6 protein solution (0.25mg/ml) containing 20mMTris-HCl (pH8.0) and 10% glycerol. | ||
Mitogen-Activated Protein Kinase 6 (MAP2K6) is a part of the dual specificity protein kinase family. MAP2K6 phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. MAP2K6 is a vital component of the MAP kinase signal transduction pathway. MAP2K6 takes part in various cellular processes such as stress induced cell cycle arrest and apoptosis.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.