Methyl 2,4-dihydroxybenzoate
(Synonyms: 2,4-二羟基苯甲酸甲酯) 目录号 : GC68159Methyl 2,4-dihydroxybenzoate 是一种活性化合物。Methyl 2,4-dihydroxybenzoate 可用于多种生化研究。
Cas No.:2150-47-2
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
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- Purity: >96.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Methyl 2,4-dihydroxybenzoate is an active compound. Methyl 2,4-dihydroxybenzoate can be used for the research of various biochemical studies[1].
[1]. N. S. Novikova, et al. Synthesis of Mesomorphic Derivatives of Methyl 2,4-Dihydroxybenzoate and Spectral and Luminescence Properties of Their Lanthanide Complexes. Russ J Gen Chem 88, 2564-2571 (2018).
Cas No. | 2150-47-2 | SDF | Download SDF |
别名 | 2,4-二羟基苯甲酸甲酯 | ||
分子式 | C8H8O4 | 分子量 | 168.15 |
溶解度 | 储存条件 | 4°C, stored under nitrogen | |
General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。 为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。 |
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Shipping Condition | 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。 |
制备储备液 | |||
1 mg | 5 mg | 10 mg | |
1 mM | 5.9471 mL | 29.7354 mL | 59.4707 mL |
5 mM | 1.1894 mL | 5.9471 mL | 11.8941 mL |
10 mM | 0.5947 mL | 2.9735 mL | 5.9471 mL |
第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量) | ||||||||||
给药剂量 | mg/kg | 动物平均体重 | g | 每只动物给药体积 | ul | 动物数量 | 只 | |||
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方) | ||||||||||
% DMSO % % Tween 80 % saline | ||||||||||
计算重置 |
计算结果:
工作液浓度: mg/ml;
DMSO母液配制方法: mg 药物溶于 μL DMSO溶液(母液浓度 mg/mL,
体内配方配制方法:取 μL DMSO母液,加入 μL PEG300,混匀澄清后加入μL Tween 80,混匀澄清后加入 μL saline,混匀澄清。
1. 首先保证母液是澄清的;
2.
一定要按照顺序依次将溶剂加入,进行下一步操作之前必须保证上一步操作得到的是澄清的溶液,可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
Synthesis of organosoluble chitosan derivatives with polyphenolic side chains
Carbohydr Polym 2012 Oct 15;90(3):1259-64.PMID:22939339DOI:10.1016/j.carbpol.2012.06.067.
A one-pot synthesis was used to produce chitosan derivatives with polyphenolic side chains via a regioselective phenolic coupling reaction. Under Mannich reaction conditions, treatment of chitosan with formaldehyde and Methyl 2,4-dihydroxybenzoate gave N-(2,6-dihydroxy-3-methoxycarbonylphenyl)methylated chitosan in good yield (87%). Formation of a CC bond occurred regioselectively at the C(3) position of Methyl 2,4-dihydroxybenzoate. Chitosan derivatives having various phenolic compounds as a side chain were easily synthesized in a similar manner. The chitosan derivatives showed good biodegradability and improved their solubility in methanol (9.8mg mL(-1)) and 2-methoxyethanol (> 10mg mL(-1)). The UV protection provided by the derivatives with phenolic benzophenone side chain was evaluated using UV spectra of polyethylene terephthalate and poly(vinyl butyral-co-vinyl alcohol-co-vinyl acetate) films coated with the derivatives and the derivatives absorbed effectively in the UV-A region (<60%). Self-aggregation of the chitosan derivatives with the phenolic side chain was observed by using a fluorescent probe in aqueous solution.
Microwave synthesis of iodine-doped bismuth oxychloride microspheres for the visible light photocatalytic removal of toxic hydroxyl-contained intermediates of parabens: catalyst synthesis, characterization, and mechanism insight
Environ Sci Pollut Res Int 2019 Oct;26(28):28871-28883.PMID:31385253DOI:10.1007/s11356-019-06074-1.
The iodine-doped bismuth oxychloride (I-doped BiOCl) microspheres are synthesized as the visible light photocatalysts for the photocatalytic removal of three toxic hydroxyl-contained intermediates of parabens. With the aid of the unique heating mode of microwave method, the I-doped BiOCl photocatalysts with tunable iodine contents and dispersed energy bands, instead of a mixture of BiOI and BiOCl or solid solution, are synthesized under the controllable conditions. Due to the stretched architectures, high specific surface area, and effective separation of photogenerated carriers, they exhibit high activity to the photocatalytic degradation of Methyl 2,4-dihydroxybenzoate (MDB), methyl 3,4-dihydroxybenzoate (MDHB), and ethyl 2,4-dihydroxybenzoate (EDB). As a typical result, it is indicated that though MDB as the most difficult intermediate of parabens to be degraded, a 91.2% removal ratio can still be achieved over the I-doped BiOCl with an energy band of 2.79 eV within 60 min. In addition, it is also confirmed that these photocatalysts remain stable throughout the photocatalytic reaction and can be reused, and more importantly, the photogenerated h+ and •O2- are the key reactive species, while •OH plays a negligible role in the photocatalytic reaction. Resorcinol was identified as the main photodegraded intermediate. These results demonstrate that this photocatalytic system not only exhibit a high efficiency but also avoid the consequent secondary pollutions due to the no formation of complex hydroxyl derivatives.