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MMP 3 Human, GST

目录号 : GP21935

Matrix Metalloproteinase-3 Human Recombinant, GST Tag

MMP 3 Human, GST Chemical Structure

规格 价格 库存 购买数量
2μg
¥2,450.00
5-10工作日
5μg
¥3,780.00
5-10工作日
10μg
¥6,860.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

Description

MMP-3 Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain fused to a GST tag containing 228 amino acids (251-478) and having a total molecular mass of 51kDa. MMP-3 is purified by proprietary chromatographic techniques.

Product Data

Purity Source Escherichia Coli.
Phycical Appearance Sterile Filtered clear solution. Shipping Condition Shipped with Ice Packs.
Synonyms Stromelysin-1; EC 3.4.24.17; Matrix metalloproteinase-3; MMP-3; Transin-1; SL-1; STMY; STR1; STMY1; MGC126102; MGC126103; MGC126104.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.
Formulation MMP-3 is supplied in 50mM Tris-Acetate, pH-7.5, 1mM EDTA and 20% Glycerol.

Introduction

MMP-3 enzyme is also known as Stromelysin-1or as Transin-1 which hydrolyzes natural collagen at physiological pH and temperature. It dissolves the intervertebral nucleus pulposus and annulus fibrosus of Herniated Lumbar Intervertebral Disk . MMP-3 hydrolyzes components of the extracellular matrix like proteoglycan, laminin, fibronectin, gelatin and collagen types III, IV and IX. It also activates pro-MMP-9 and pro-MMP-8 and superactivates plasmin activated MMP-1. MMP-3 is secreted as a latent proenzyme and is activated by a variety of proteinases, e.g. plasmin, trypsin, chymotrypsin, cathepsin G or human neutrophil elastase. MMP-3 was found to be capable of activating the precursor of IL1-beta.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.

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