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MRPL48 Human

目录号 : GP23957

Mitochondrial Ribosomal Protein L48 Human Recombinant

MRPL48 Human Chemical Structure

规格 价格 库存 购买数量
5μg
¥840.00
5-10工作日
20μg
¥2,030.00
5-10工作日
1mg
¥37,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

Description

MRPL48 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 207 amino acids (29-212 a.a) andhaving a molecular mass of 23.1kDa.MRPL48 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 85% as determined by SDS-PAGE. Source Escherichia Coli.
Phycical Appearance Sterile Filtered clear solution. Shipping Condition Shipped with Ice Packs.
Synonyms Mitochondrial Ribosomal Protein L48; MRP-L48; L48MT; 39SRibosomal Protein L48; Mitochondrial; CGI-118; HSPC290; 39S ribosomal proteinL48; mitochondrial.
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSSGEKPIY SVGGILLSIS RPYKTKPTHG IGKYKHLIKA EEPKKKKGKVEVRAINLGTD YEYGVLNIHL TAYDMTLAES YAQYVHNLCN SLSIKVEESY AMPTKTIEVL QLQDQGSKMLLDSVLTTHER VVQISGLSAT FAEIFLEIIQ SSLPEGVRLSVKEHTEEDFK GRFKARPELE ELLAKLK.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation MRPL48 protein solution (1 mg/ml) containing 20mMTris-HCl buffer (pH 8.0) and 10% glycerol.

Introduction

Mitochondrial Ribosomal Protein L48, also known as MRPL48, is amammalian mitochondrial ribosomal protein which assists in protein synthesiswithin the mitochondrion. Mitochondrial ribosomes, mitoribosomes, consist of asmall 28S subunit and a large 39S subunit. They include an estimated 75%protein to rRNA composition while comparing to prokaryotic ribosomes, wherethis ratio is reversed.An additional dissimilarity between mammalian mitoribosomes & prokaryoticribosomes is that the latter contain a 5S rRNA. Between different species, theproteins containing the mitoribosome differ very much in sequence, as well as inbiochemical properties from time to time, which prevents easy recognition throughsequence homology. MRPL48 encodes a 39S subunit protein. A pseudogenecorresponding to MRPL48 is found on chromosome 6p.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

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