MUC1 Human
目录号 : GP26311The Human Mucin-1 (CA15-3) is having a molecular mass of approximately 400kDa, and was purified from human carcinoma cell line
Sample solution is provided at 25 µL, 10mM.
The Human Mucin-1 (CA15-3) is having a molecular mass of approximately 400kDa, and was purified from human carcinoma cell line.
Purity | Greater than 60%. | Source | Human carcinoma cell line. |
Phycical Appearance | Clear to opalescent colorless frozen solution. | Shipping Condition | withIcePacks |
Stability | Human MUC1 although stable at 4°C for 1 week, should be stored at -20°C. | ||
Formulation | MUC1 is supplied in a 0.05M sodium phosphate buffer, pH 7.5, 0.09% NaN3 and 0.15M NaCl. |
Human Mucin-1 (CA15-3), aka MUC1, is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. This protein has alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit roles in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Mucins line the apical surface of epithelial cells in the stomach, lungs, intestines, eyes and other tissues. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain, preventing the pathogen from reaching the cell surface. Overexpression of CA15-3 is often associated with colon, breast, ovarian, lung and pancreatic cancers.
Human MUC1 although stable at 4°C for 1 week, should be stored at -20°C.