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MUC1 Human

目录号 : GP26311

The Human Mucin-1 (CA15-3) is having a molecular mass of approximately 400kDa, and was purified from human carcinoma cell line

MUC1 Human Chemical Structure

规格 价格 库存 购买数量
10KU
¥13,860.00
现货
25KU
¥26,600.00
现货
50KU
¥42,000.00
现货

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Sample solution is provided at 25 µL, 10mM.

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产品描述

The Human Mucin-1 (CA15-3) is having a molecular mass of approximately 400kDa, and was purified from human carcinoma cell line.

Product Data

Purity Greater than 60%. Source Human carcinoma cell line.
Phycical Appearance Clear to opalescent colorless frozen solution. Shipping Condition withIcePacks
Stability Human MUC1 although stable at 4°C for 1 week, should be stored at -20°C.
Formulation MUC1 is supplied in a 0.05M sodium phosphate buffer, pH 7.5, 0.09% NaN3 and 0.15M NaCl.

Introduction

Human Mucin-1 (CA15-3), aka MUC1, is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. This protein has alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit roles in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Mucins line the apical surface of epithelial cells in the stomach, lungs, intestines, eyes and other tissues. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain, preventing the pathogen from reaching the cell surface. Overexpression of CA15-3 is often associated with colon, breast, ovarian, lung and pancreatic cancers.

Stability

Human MUC1 although stable at 4°C for 1 week, should be stored at -20°C.