Myomodulin A (Aplysia, Lymnaea) (trifluoroacetate salt)
(Synonyms: MMa,Pro-Met-Ser-Met-Leu-Arg-Leu-NH2) 目录号 : GC91816Myomodulin A is a gastropod neuropeptide.
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Myomodulin A is a gastropod neuropeptide.[1] It is found in gastropod ventral lobe neurons, neural elements of the accessory radula closer (ARC) muscle, and penis nerve.1,2,3 Myomodulin A is biosynthesized by ARC motor neurons in A. californica and potentiates motor neuron-elicited contractions of the A. californica buccal mass ARC.[2] Myomodulin A also increases the relaxation rate of electrically evoked muscle contractions in L. stagnalis penis retractor muscle.[3]
References:
[1].Miller, M.W., Beushausen, S., Vitek, A., et al.The myomodulin-related neuropeptides: Characterization of a gene encoding a family of peptide cotransmitters in AplysiaJ. Neurosci.13(8)3358-3367(1993).
[2].Cropper, E.C., Tenenbaum, R., Kolks, M.A., et al.Myomodulin: a bioactive neuropeptide present in an identified cholinergic buccal motor neuron of AplysiaProc. Natl. Acad. Sci. USA84(15)5483-5486(1987).
[3].Li, K.W., van Golen, F.A., van Minnen, J., et al.Structural identification, neuronal synthesis, and role in male copulation of myomodulin-A of Lymnaea: A study involving direct peptide profiling of nervous tissue by mass spectrometryBrain Res. Mol. Brain Res.25(3-4)355-358(1994).
| 制备储备液 | |||
 |
1 mg | 5 mg | 10 mg |
| 1 mM | 1.1819 mL | 5.9095 mL | 11.8189 mL |
| 5 mM | 0.2364 mL | 1.1819 mL | 2.3638 mL |
| 10 mM | 0.1182 mL | 0.5909 mL | 1.1819 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。