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N-cis-tetradec-9Z-enoyl-L-Homoserine lactone Sale

(Synonyms: C14:1Δ9cis(L)HSL, N(2oxotetrahydrofuran3Syl) Myristoleyl Amide) 目录号 : GC44337

A bacterial quorum-sensing signaling molecule

N-cis-tetradec-9Z-enoyl-L-Homoserine lactone Chemical Structure

Cas No.:1675245-06-3

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5mg
¥633.00
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10mg
¥1,199.00
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25mg
¥2,861.00
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50mg
¥5,072.00
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Sample solution is provided at 25 µL, 10mM.

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产品描述

Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). AHLs vary in acyl group length (C4-C18), in the substitution of C3 (hydrogen, hydroxyl, or oxo group) and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family. C14:1-δ9-cis-(L)-HSL is a long-chain AHL that functions as a signaling molecule in the quorum sensing of A. vitis. Regulating bacterial quorum sensing signaling can be used to inhibit pathogenesis and thus, represents a new approach to antimicrobial therpy in the treatment of infectious diseases.

Chemical Properties

Cas No. 1675245-06-3 SDF
别名 C14:1Δ9cis(L)HSL, N(2oxotetrahydrofuran3Syl) Myristoleyl Amide
Canonical SMILES CCCC/C=C\CCCCCCCC(=O)N[C@H]1CCOC1=O
分子式 C18H31NO3 分子量 309.4
溶解度 DMF: 20 mg/ml,DMSO: 20 mg/ml,DMSO:PBS(pH7.2) 1:1: 0.5 mg/ml,Ethanol: 2 mg/ml 储存条件 Store at -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 3.2321 mL 16.1603 mL 32.3206 mL
5 mM 0.6464 mL 3.2321 mL 6.4641 mL
10 mM 0.3232 mL 1.616 mL 3.2321 mL
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