Home>>NMDAR-TRPM4 blocker C19 dihydrochloride - FMP-A-02 | Aliudanexin

NMDAR-TRPM4 blocker C19 dihydrochloride - FMP-A-02 | Aliudanexin

目录号 : GB40296

C19 is an NMDAR/TRPM4 (N/T) interaction interface inhibitor with an IC50 value of 1.1 μM for NMDA-induced cell death in hippocampal neurons. This inhibitor strongly reduced NMDA-triggered toxicity and mitochondrial dysfunction, abolished cyclic adenosine monophosphate-responsive element-binding protein (CREB) shutoff, boosted gene induction, and reduced neuronal loss in mouse models of stroke and retinal degeneration. Potent neuroprotectant.NMDAR-TRPM4 blocker C8 is available as NMDAR-TRPM4 blocker C8 dihydrochloride.

NMDAR-TRPM4 blocker C19 dihydrochloride - FMP-A-02 | Aliudanexin Chemical Structure

Cas No.:2241128-93-6

规格 价格 库存 购买数量
10mg
¥4,290.00
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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

C19 is an NMDAR/TRPM4 (N/T) interaction interface inhibitor with an IC50 value of 1.1 μM for NMDA-induced cell death in hippocampal neurons. This inhibitor strongly reduced NMDA-triggered toxicity and mitochondrial dysfunction, abolished cyclic adenosine monophosphate-responsive element-binding protein (CREB) shutoff, boosted gene induction, and reduced neuronal loss in mouse models of stroke and retinal degeneration. Potent neuroprotectant.NMDAR-TRPM4 blocker C8 is available as NMDAR-TRPM4 blocker C8 dihydrochloride.

Chemical Properties

Cas No. 2241128-93-6 SDF Download SDF
分子式 C13H16Cl3N3O.2HCl 分子量 409.57
溶解度 储存条件
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溶解性数据

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1 mg 5 mg 10 mg
1 mM 2.4416 mL 12.2079 mL 24.4159 mL
5 mM 0.4883 mL 2.4416 mL 4.8832 mL
10 mM 0.2442 mL 1.2208 mL 2.4416 mL
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