Normeperidine-d4 (hydrochloride) (CRM)
(Synonyms: Norpethidine-d4) 目录号 : GC48845A Certified Reference Material
Cas No.:2749394-90-7
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Normeperidine-d4 (hydrochloride) (CRM) is a certified reference material intended for use as an internal standard for the quantification of normeperidine by GC- or LC-MS. Normeperidine is structurally categorized as an opioid. It is both a metabolite of and a precursor to meperidine , an opioid analgesic that is commonly abused.1,2 Normeperidine is regulated as a Schedule II compound in the United States. This product is intended for research and forensic applications.
1.Ossipov, M.H., Harris, S., Lloyd, P., et al.Antinociceptive interaction between opioids and medetomidine: Systemic additivity and spinal synergyAnesthesiology73(6)1227-1235(1990) 2.Atluri, S.A., Sudarshan, G., and Manchikanti, L.Assessment of the trends in medical use and misuse of opioid analgesics from 2004 to 2011Pain Physician17(2)E119-E128(2014)
Cas No. | 2749394-90-7 | SDF | |
别名 | Norpethidine-d4 | ||
Canonical SMILES | O=C(OCC)C1(C2=CC=CC=C2)C([2H])([2H])CNCC1([2H])[2H].Cl | ||
分子式 | C14H15D4NO2•HCl | 分子量 | 273.8 |
溶解度 | 储存条件 | -20°C | |
General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。 为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。 |
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Shipping Condition | 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。 |
制备储备液 | |||
1 mg | 5 mg | 10 mg | |
1 mM | 3.6523 mL | 18.2615 mL | 36.523 mL |
5 mM | 0.7305 mL | 3.6523 mL | 7.3046 mL |
10 mM | 0.3652 mL | 1.8262 mL | 3.6523 mL |
第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量) | ||||||||||
给药剂量 | mg/kg | 动物平均体重 | g | 每只动物给药体积 | ul | 动物数量 | 只 | |||
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方) | ||||||||||
% DMSO % % Tween 80 % saline | ||||||||||
计算重置 |
计算结果:
工作液浓度: mg/ml;
DMSO母液配制方法: mg 药物溶于 μL DMSO溶液(母液浓度 mg/mL,
体内配方配制方法:取 μL DMSO母液,加入 μL PEG300,混匀澄清后加入μL Tween 80,混匀澄清后加入 μL saline,混匀澄清。
1. 首先保证母液是澄清的;
2.
一定要按照顺序依次将溶剂加入,进行下一步操作之前必须保证上一步操作得到的是澄清的溶液,可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。