NRG1-beta 1 Protein, Human
目录号 : GC26535NRG-1 蛋白, Human属于结构相关的多肽生长因子家族，来源于选择性剪接基因，诱导 Fn14 在 MCF7 细胞中表达。
Sample solution is provided at 25 µL, 10mM.
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NRG-1 蛋白, Human属于结构相关的多肽生长因子家族，来源于选择性剪接基因，诱导 Fn14 在 MCF7 细胞中表达。
| Purity | Greater than 95% as determined by reducing SDS-PAGE. | Source | E. coli |
| Phycical Appearance | Aseptic powder | Shipping Condition | Room temperature in continental US; may vary elsewhere. |
| Synonyms | 重组人调蛋白-1 β1; rHuHeregulin-1 β1; ARIA; HRG; NRG1; Neuregulin-1 | ||
| Amino Acid Sequence | SHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEAE | ||
| Solubility | It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose). | ||
| Apparent Molecular Weight | Approximately 8 kDa | ||
| Biological Activity | Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer cells. The ED50 this effect is ≤ 2.158 ng/mL, corresponding to a specific activity is ≥ 4.6339×105 units/mg. | ||
| Formulation | Lyophilized from sterile PBS or 50 mM Tris-HCL, 300 mM NaCl, 200 mM arginine, pH 8.0. | ||
NRG-1 Protein, Human belongs to a family of structurally-related polypeptide growth factors derived from alternatively spliced genes, induces Fn14 expression in MCF7 cells.
Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer cells. The ED50 this effect is ≤ 2.158 ng/mL, corresponding to a specific activity is ≥ 4.6339×105 units/mg.