Palmitoleic Acid methyl ester
(Synonyms: 棕榈油酸甲酯,(Z)-Methyl hexadec-9-enoate; Methyl cis-9-Hexadecenoate) 目录号 : GC41581
An ω-7 fatty acid methyl ester
Cas No.:1120-25-8
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Palmitoleic acid methyl ester is an ester version of palmitoleic acid , an ω-7 monounsaturated fatty acid that is a common constituent of the triglycerides of human adipose tissue. Palmitoleic acid-based diets raise low-density lipoprotein (LDL) cholesterol and lower high-density lipoprotein (HDL) cholesterol, even when dietary intake of cholesterol is maintained at a low level. Methyl esters of fatty acids are commonly used for the formulation of fatty acid-containing diets and dietary supplements.
| Cas No. | 1120-25-8 | SDF | |
| 别名 | 棕榈油酸甲酯,(Z)-Methyl hexadec-9-enoate; Methyl cis-9-Hexadecenoate | ||
| Canonical SMILES | CCCCCC/C=C\CCCCCCCC(OC)=O | ||
| 分子式 | C17H32O2 | 分子量 | 268.4 |
| 溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: > 50 mg/ml | 储存条件 | Store at -20°C |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
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| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 3.7258 mL | 18.6289 mL | 37.2578 mL |
| 5 mM | 0.7452 mL | 3.7258 mL | 7.4516 mL |
| 10 mM | 0.3726 mL | 1.8629 mL | 3.7258 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
Lotus (Nelumbo nuficera) flower essential oil increased melanogenesis in normal human melanocytes
Exp Mol Med 2009 Jul 31;41(7):517-25.PMID:19322028DOI:10.3858/emm.2009.41.7.057.
In this study, the essential oil from lotus flower extract, including petals and stamens, was assessed with regard to its effects on melanogenesis in human melanocytes. The lotus flower essential oil was shown to stimulate melanin synthesis and tyrosinase activity in a dose-dependent manner. The lotus flower essential oil induced the expression of tyrosinase, microphthalmia-associated transcription factor M (MITF-M), and tyrosinase-related proten-2 (TRP-2) proteins, but not tyrosinase mRNA. Moreover, it increased the phosphorylation of ERK and cAMP response element binding protein (CREB). In order to verify the effective components of the lotus flower oil, its lipid composition was assessed. It was found to be comprised of palmitic acid methyl ester (22.66%), linoleic acid methyl ester (11.16%), Palmitoleic Acid methyl ester (7.55%) and linolenic acid methyl ester (5.16%). Among these components, palmitic acid methyl ester clearly induced melanogenesis as the result of increased tyrosinase expression, thereby indicating that it may play a role in the regulation of melanin content. Thus, our results indicate that lotus flower oil may prove useful in the development of gray hair prevention agents or tanning reagents.
Garlic Allelochemical Diallyl Disulfide Alleviates Autotoxicity in the Root Exudates Caused by Long-Term Continuous Cropping of Tomato
J Agric Food Chem 2020 Oct 21;68(42):11684-11693.PMID:32991155DOI:10.1021/acs.jafc.0c03894.
Continuous cropping obstacles seriously affect the sustainable production of tomatoes (Solanum lycopersicum L.). Researchers have found that intercropping with garlic (Allium sativum L.) could alleviate tomato continuous cropping obstacles. Diallyl disulfide (DADS) is the main allelochemical in garlic. However, the mechanism of DADS in alleviating tomato continuous cropping obstacles is still unknown. In this research, aqueous extracts of tomato continuous cropping soil were used to simulate the continuous cropping condition of tomato. Our results showed that DADS increased root activity and chlorophyll content and improved the activity of antioxidant enzymes (superoxide dismutase (SOD), peroxidase (POD), and phenylalanine ammonia-lyase (PAL)) and the metabolism of nonenzymatic antioxidants (glutathione (GSH) and oxidized glutathione (GSSG)) in tomato plants. DADS treatment reduced the content of fatty acid esters in tomato root exudates (e.g., palmitate methyl ester, Palmitoleic Acid methyl ester, oleic acid methyl ester) and increased the level of substances such as dibutyl phthalate and 2,2'-methylenebis(6-tert-butyl-4-methylphenol). The higher concentrations of palmitate methyl ester inhibited tomato hypocotyl growth, while oleic acid methyl ester inhibited tomato root growth. Moreover, the application of DADS significantly inhibited the secretion of these esters in the root exudates. Therefore, it suggests that DADS may increase tomato resistance and promote tomato plant growth by increasing root activity and photosynthetic capacity and development to reduce autotoxicity of tomato.