PCOLCE Human
目录号 : GP22052Procollagen C-Endopeptidase Enhancer Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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PCOLCE Human Recombinant produced in E.Coli is a single, non-glycosylatedpolypeptide chain containing 447 amino acids (26-449 a.a) and having amolecular mass of 47.9kDa.PCOLCE is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.
| Purity | Greater than 85.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | ProcollagenC-Endopeptidase Enhancer; Procollagen C-Proteinase Enhancer 1; Type IProcollagen COOH-Terminal Proteinase Enhancer; Type 1 Procollagen C-ProteinaseEnhancer Protein; Procollagen COOH-Terminal Proteinase Enhancer 1; PCPE-1; PCPE1;Procollagen; Type 1; COOH-Terminal Proteinase Enhancer; ProcollagenC-Endopeptidase Enhancer 1; COOH-Terminal Proteinase Enhancer; Procollagen;Type 1; PCPE; Procollagen C-endopeptidase enhancer 1. | ||
| Amino Acid Sequence | MGSSHHHHHHSSGLVPRGSH MGSQTPNYTRPVFLCGGDVK GESGYVASEG FPNLYPPNKE CIWTITVPEG QTVSLSFRVF DLELHPACRY DALEVFAGSGTSGQRLGRFC GTFRPAPLVA PGNQVTLRMT TDEGTGGRGF LLWYSGRATS GTEHQFCGGR LEKAQGTLTTPNWPESDYPP GISCSWHIIA PPDQVIALTF EKFDLEPDTY CRYDSVSVFN GAVSDDSRRL GKFCGDAVPGSISSEGNELL VQFVSDLSVT ADGFSASYKT LPRGTAKEGQ GPGPKRGTEP KVKLPPKSQP PEKTEESPSAPDAPTCPKQC RRTGTLQSNF CASSLVVTAT VKSMVREPGE GLAVTVSLIG AYKTGGLDLP SPPTGASLKFYVPCKQCPPM KKGVSYLLMG QVEENRGPVL PPESFVVLHR PNQDQILTNL SKRKCPSQPV RAAASQD. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | PCOLCE protein solution (1mg/ml) containing 20mM Tris-HClbuffer (pH 8.0) and 10% glycerol. | ||
Procollagen C-endopeptidase enhancer 1, also known as PCOLCE binds tothe C-terminal propeptide of type I procollagen and enhances procollagenC-proteinase activity. In addition, C-terminal processed part of PCPE (CT-PCPE)has a metalloproteinase inhibitory activity. Among the diseases which are associatedwith PCOLCE: bone fracture & oculopharyngeal muscular dystrophy.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.