PDCD1LG2 Human
目录号 : GP24145Programmed Cell Death 1 Ligand 2 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
PDCD1LG2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 204 amino acids (20-200 a.a.) and having a molecular mass of 22.8kDa.PDCD1LG2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Purity | Greater than 90% as determined by SDS-PAGE. | Source | E.coli. |
Phycical Appearance | Sterile Filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
Synonyms | Programmed cell death 1 ligand 2; PD-1 ligand 2; PD-L2; PDCD1 ligand 2; Programmed death ligand 2; PDCD1LG2; B7-DC; Butyrophilin B7-DC; CD273; B7DC; CD273; PDCD1L2; PDL2; bA574F11.2; Btdc. | ||
Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSLFTVTVP KELYIIEHGS NVTLECNFDT GSHVNLGAIT ASLQKVENDT SPHRERATLL EEQLPLGKAS FHIPQVQVRD EGQYQCIIIY GVAWDYKYLT LKVKASYRKI NTHILKVPET DEVELTCQAT GYPLAEVSWP NVSVPANTSH SRTPEGLYQV TSVLRLKPPP GRNFSCVFWN THVR. | ||
Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
Formulation | PDCD1LG2 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 0.4M Urea and 10% glycerol. |
Programmed cell death 1 ligand 2 (PDCD1LG2) which takes part in the costimulatory signal, is necessary for T-cell proliferation. PDCD1LG2 is also involved in IFNG production in a PDCD1-independent way. The interaction with PDCD1 inhibits T-cell proliferation by preventing cytokine production and cell cycle progression.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.