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PDGF A Human

目录号 : GP20812

Platelet-Derived Growth Factor A Human Recombinant

PDGF A Human Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-7工作日
10μg
¥2,030.00
5-7工作日
1mg
¥72,800.00
5-7工作日

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Sample solution is provided at 25 µL, 10mM.

Description

Platelet-Derived Growth Factor A Human Recombinant short chain produced in E.Coli is a non-glycosylated, polypeptide chain containing 110 amino acids fragment (87-196) and having a total Mw of 17.02kDa, with an amino-terminal hexahistidine tag. PDGF-A is purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 95.0% as determined by SDS-PAGE. Source Escherichia Coli.
Phycical Appearance Sterile Filtered clear solution. Shipping Condition Shipped with Ice Packs.
Synonyms Glioma-derived growth factor; GDGF; Osteosarcoma-derived Growth Factor; ODGF; PDGF-A; PDGF-1.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.
Formulation Platelet-derived Growth Factor A is supplied in 25mM Na-Acetate, pH-4.8, 1mM EDTA and 50% glycerol.

Introduction

The term боPDGFбп refers to a family of disulphide bond-linked dimeric isoforms that act as autocrine and paracrine growth factors and are produced by a variety of cell types other than platelets.They act as potent mitogens for almost all mesenchymally-derived cells. Aberrant expression is involved in certain cancers, fibroproliferative disorders and atherosclerosis. The protein also contributes to wound healing and neural regeneration. There are four members of the PDGF family иC PDGF A, PDGF B, PDGF C and PDGF D. Two distinct types of PDGF-A exist иC a short form that is soluble and a long form that is retained by the extracellular matrix.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.

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